Artesunate has been recommended by the World Health Organization (WHO) as the first-line treatment for severe malaria since 2010. It is not licensed in the United States but is available from CDC under an investigational new drug (IND) protocol. During 2010-2012, a total of 19 cases of delayed hemolytic anemia after treatment of severe malaria with artesunate were published in the peer-reviewed...

idiopathic acquired hemolytic atsemia, Group II, hemolytic atsemia followitsg irus pmseumomsia and Group III, chrotsic hemolytic atsemia with hemoglohitsuria and Raynaud’s phemsomena. A detailed accoumst. of the climsical aspects of tise three patients of Group III was published by Ferrimams, Dacie, Keele amid Fullerton2 who also made an amsalysis of msine similar cases reported in the literatu...

Objectives We studied the involvement of serum-complement (C') and oxidative stress in the hemolytic anemias Paroxysmal Nocturnal Hemoglobinuria (PNH) and Auto-Immune Hemolytic Anemia (AIHA), and the effect of Fermented Papaya Preparation (FPP), an antioxidant-containing yeast fermentation product of Carica papaya Linn. Methodology Normal human red blood cells (RBC) treated with the sulphydryl ...

Hemosiderinuria caused by intravascular hemolysis is a characteristic clinical feature of an acquired hemolytic disorder, paroxysmal nocturnal hemoglobinuria (PNH). We examined the deposition of hemosiderin (iron) in the kidneys of 6 patients with PNH using magnetic resonance imaging (MRI). Three patients with autoimmune hemolytic anemia (AIHA), a hemolytic disorder showing extravascular hemoly...

Abstract Mothballs are a common household item used as repellents and deodorizers. They potential hazards rare agents of poisoning in children. composed mainly naphthalene, camphor, 1, 4-dichlorobenzene varying amounts depending on the manufacturers. It is essential to rule out by naphthalene children presenting with hemolysis eliciting proper history. Since mothballs readily available at home,...

By WILLIAM H. CROSBY, MAJOR, MC, AUS P AROXYSMAL nocturnal hemoglobinuria (Marchiafava-Micheli syndrome) is a rare form of chronic hemolytic anemia characterized by the presence of abnormal erythrocytes which are susceptible to lysis by a factor normally present in plasma or serum. It has recently been suggested that this factor resembles closely or may even be identical with the coagulation ac...

By J. D. FELDMAN, M. RACHMILEWITZ AND 0. STEIN I N THE COURSE OF STUDYING THE EFFECT of the adrenal cortex and its hormones omi hemolysis, a uniform pattern of beukocyte response was noted.’2 ‘ 13 The reaction consisted of marked leukocytosis, neutrophilia amid eosimiophibia throughout the period of red cell destruction. A search of the medical literature oh this aspect of hemolysis revealed a ...

A patient undergoing chemotherapy for relapsed non Hodgkin lymphoma developed tumor lysis syndrome, hypoxia and the abrupt onset of intravascular hemolysis. A past history of unexplained anemia and the finding of blister cells on peripheral smear led to the suspicion of congenital glucose phosphate dehydrogenase (G6PD) deficiency with intravascular hemolysis induced by the drug rasburicase. G6P...

Glucose-6-phosphate (G6PD) deficiency is the most common human enzyme defect, often presenting with neonatal jaundice and/or acute hemolytic anemia, triggered by oxidizing agents. G6PD deficiency is an X-linked, hereditary disease, mainly affecting men, but should also be considered in females with an oxidative hemolysis.

idiopathic acquired hemolytic atsemia, Group II, hemolytic atsemia followitsg irus pmseumomsia and Group III, chrotsic hemolytic atsemia with hemoglohitsuria and Raynaud’s phemsomena. A detailed accoumst. of the climsical aspects of tise three patients of Group III was published by Ferrimams, Dacie, Keele amid Fullerton2 who also made an amsalysis of msine similar cases reported in the literatu...