In modern medical practice, toxicity studies are essential in assessment of safety of extracts or drugs used in clinical medicine. The interaction of the toxin or its metabolite with cellular constituents may bring about significant changes in hematological parameters. These alterations may be rapid or slow and often cause a change in structure and function of the affected tissues. In clinical ...

The aim of this study was to examine the adverse effects of zinc nanoparticles on hematological indices of trout and investigate the improvement of these indices after vitamin C treatments. This study assesses the protective role of vitamin C in fish exposed to ZnO NPs. Two concentrations of ZnO-NPs (40 and 80 mg L-1) and two doses of vitamin C (400 and 800 mg per kg of feed) were used to treat...

The aim of this study was to investigate the effect of seasonal variation on the haematological and biochemical parameters in adult wild Jerboa (Jaculus jaculus) in Saudi Arabia. Blood samples of 40 Jerboa were collected in January and August for analyzing hematological and biochemical parameters. In hematological parameters, haemoglobin, mean corpuscular haemoglobin (MCH), mean corpuscular hae...

background because of varying reports, there is still need to investigate the impact of wrestling on hematological indices. objectives we investigated differences in the basic hematological indices in wrestlers compared to sedentary controls. patients and methods the blood samples containing anticoagulant were collected from 12 male elite wrestlers (age = 24 ± 1.2 years, weight = 76 ± 5 kg) wit...

Background: The double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. In addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. Materials and Methods: An Iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulpl...

abstract background: thalassemias are the most common inherited blood disorders caused by some mutations which can reduce the synthesis of globin chains. iron overload and its organ deposition are responsible for functional abnormalities and tissue injury in patients who affected by β-thalassemia major. the aim of this case-control study was evaluation of hematological parameters, oxidative str...