maltophilia Bacteremia in Patients with Hematologic Malignancies Sun Young Cho, MD; Cheol-in Kang, MD; Jae-Hoon Ko, MD; Eun-Jeong Joo, MD; Doo Ryeon Chung, MD; Kyong Ran Peck, MD; Nam Yong Lee, MD, PhD; JaeHoon Song; Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Division of Infectious Diseases, Samsung Medical Center, Se...

RNA splicing is a key regulatory step in the proper control of gene expression. It highly dynamic process orchestrated by spliceosome, macro-molecular machinery that consists protein and components. The dysregulation has been observed many human pathologies ranging from neurodegenerative diseases to cancer. recent identification recurrent mutations core components spliceosome hematologic malign...

in this session, we will discuss 7 cases in pediatric musculoskeletal field. these cases will include different aspects of bone and msk disorders in pediatrics such as bone tumors (benign and malignant), bone involvement in metabolic and hematologic disorders, infectious diseases and soft tissue vascular lesions. during this session, we will ask some volunteered radiology residents to explain t...

H-ferritin (HF) is a core subunit of the iron storage protein ferritin and is related to the pathogenesis of malignant diseases. HF overexpression is present in human hematologic malignancies, suggesting that HF overexpression may contribute to the development of hematologic cancers. However, in vivo evidence that HF is directly linked to hematologic tumorigenesis has not yet been shown. In thi...

T HE MODERN ERA ofprenatal testing for hematologic diseases began in 1974. Prior to that time, the only test available consisted of determination of fetal sex following amniocentesis in cases at risk for sex-linked disorders, such as the hemophilias. Methods for obtaining fetal blood in utero in ongoing pregnancies were initiated in 1974, and these developments led to the possibility of prenata...

T HE MODERN ERA ofprenatal testing for hematologic diseases began in 1974. Prior to that time, the only test available consisted of determination of fetal sex following amniocentesis in cases at risk for sex-linked disorders, such as the hemophilias. Methods for obtaining fetal blood in utero in ongoing pregnancies were initiated in 1974, and these developments led to the possibility of prenata...

T HE MODERN ERA ofprenatal testing for hematologic diseases began in 1974. Prior to that time, the only test available consisted of determination of fetal sex following amniocentesis in cases at risk for sex-linked disorders, such as the hemophilias. Methods for obtaining fetal blood in utero in ongoing pregnancies were initiated in 1974, and these developments led to the possibility of prenata...

T HE MODERN ERA ofprenatal testing for hematologic diseases began in 1974. Prior to that time, the only test available consisted of determination of fetal sex following amniocentesis in cases at risk for sex-linked disorders, such as the hemophilias. Methods for obtaining fetal blood in utero in ongoing pregnancies were initiated in 1974, and these developments led to the possibility of prenata...

<1 case/100,000 population/year, and the disease accounts for ≈2%–3% of all leukemias in adults in the United States (8). Infections are a common complication for patients with this disease (10). These 2 cases of imported melioidosis show that travelers with hematologic malignancies are at risk for such infections (1). Immunocompromised travelers might be first sentinels for ongoing endemic dis...