BACKROUND Transcatheter pulmonary valve replacement is currently performed in clinical trials, however limited by the use of glutaraldehyde treated bioprostheses. This feasibility study was performed to evaluate delivery-related tissue distortion during implantation of a tissue engineered (TE) heart valves. MATERIAL AND METHOD The injectable TE heart valve was mounted on a self-expanding niti...

Presentation Preference: Oral or Poster Objectives: Carbohydrate loading (CL) is an accepted component of general surgery ERAS protocols. The role of nutritional supplementation within hip and knee replacement ERAS is unclear. This review examines the evidence for nutritional supplements accelerating achievement of discharge criteria. Methods: Table 1 details the literature search Results: Psyc...

BACKGROUND Tissue-engineered or decellularized heart valves have already been implanted in humans or are currently approaching the clinical setting. The aim of this study was to examine the migratory response of human monocytic cells toward decellularized porcine and human heart valves, a pivotal step in the early immunologic reaction. METHODS AND RESULTS Porcine and human pulmonary valve con...

Heart valve (HV) culture is one of the major Duke criteria for the diagnosis of definite infectious endocarditis (IE). However, previous series suggest that heart valve culture does not have good sensitivity (7.8 to 17.6%) and may be contaminated during manipulation. Our goal was to establish the value of routine cultures of heart valves in patients with and without IE. From 2004 to 2006, resec...

j-Ieart size was measured radiographically before and after single or double homograft valve replacement in 69 consecutive patients. Thirty patients had aortic valve replacement, 25 mitral, and 14 both aortic and mitral valve replacement. For aortic valve replacement a fresh unsupported homograft was inserted in the subcoronary position, while for mitral valve replacement afresh semilunar homog...

Heart disease, including valve pathologies, is the leading cause of death worldwide. Despite the progress made thanks to improving transplantation techniques, a perfect valve substitute has not yet been developed: once a diseased valve is replaced with current technologies, the newly implanted valve still needs to be changed some time in the future. This situation is particularly dramatic in th...

there is a paucity of literature regarding iatrogenic aortic valve perforation after cardiac operation is performed in the vicinity of the aortic valve. this report describes the clinical, echocardiographic, and angiocardiographic recognition of iatrogenic aortic valve perforation in a patient who had previously under gone membranous ventricular septal defect and pulmonary stenosis. five days a...

Gaasch WH, Lytle BW, Nishimura RA, O’Gara PT, O’Rourke RA, Otto CM, Shah PM, Shanewise JS. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease. Circulation 2006;114:84–231. 5. Bodnar E. The Medtronic Parallel (TM) valve and the lessons learned. J Heart Valve Dis 1996;5:572–573. 6. Van Nooten GJ, Van Belleghem Y, Caes F, François K, Van Overbeke H, Bové T, Taeymans...

OBJECTIVE A challenging issue is to create a heart valve with growth and remodeling potential, which would be of great interest for congenital heart valve surgery. This study was performed to evaluate the growth and remodeling potentials of a decellularized heart valve. METHODS In 4 juvenile sheep (age 12 +/- 1 weeks) with a weight of 24.3 +/- 4.4 kg, a 17-mm diameter decellularized porcine v...

Between 1998 and 2004 approximately 400,000 people died in Germany from cardiovascular disease, with heart valve disease playing a significant role. Heart valve disease can lead to stenoses or insufficiency. In 2006, heart valve operations nationwide increased to 20,000. The implantation of heart valves demands great skill and experience of the heart surgeon. To date, location of implantation w...