INTRODUCTION Hypertension and hyperlipidemia are major cardiovascular disease risk factors. To modify them, patients often need to adopt healthier lifestyles and adhere to prescribed medications. However, patients' adherence to recommended treatments has been suboptimal. Reducing out-of-pocket costs (ROPC) to patients may improve medication adherence and consequently improve health outcomes. Th...

Milan, Italy Cost-Effectiveness Analysis of Peginterferon Beta-1a in Italian Relapsing-Remitting Multiple Sclerosis Management Iannazzo S,1 Santoni L,2 Saleri C,2 Puma E,2 Vestri G,2 Giuliani L,1 Canonico PL,3 Centonze D4 1SIHS Health Economics Consulting, Torino, Italy; 2Biogen Italia, Milan, Italy; 3Department of Pharmaceutical Sciences, University of Eastern Piedmont, Novara, Italy; 4Centre ...

OBJECTIVE The purpose of this analysis is to evaluate the cost-effectiveness of belimumab, a new biological treatment specifically developed for the treatment of Systemic Lupus Erythematosus (SLE), in the Italian setting. SLE is a chronic non-organ specific autoimmune disease characterized by a disregulation of the immune system that involves many organs and systems. METHODS A cost-effectiven...

We read with great pleasure ISPOR’s new journal, Value in Health Regional Issues, which had been devoted to the regions of Central and Eastern Europe, Western Asia, and Africa (CEEWAA) [1]. We do believe that ISPOR’s strategic decision on releasing this journal and providing space for scholars from less developed regions of the world for publishing their findings in the field of health economic...

OBJECTIVE We estimated the investment needs, population health gains, and cost-effectiveness of different policy options for scaling-up prevention and treatment of HIV in the 10 countries that currently comprise 80% of all people living with HIV in sub-Saharan Africa (Ethiopia, Kenya, Malawi, Mozambique, Nigeria, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe). DESIGN We adapted the est...

The American College of Physicians recently highlighted the need to provide increased information comparing the effectiveness of health care interventions to ensure the rational and effective practice of medicine. Comparative effectiveness refers to the evaluation of the relative clinical effectiveness, safety, and cost of 2 or more medical services, drugs, devices, therapies, or procedures use...

Potential cost-effective barriers in cost-effectiveness studies mean that budgetary impact analyses should also be included in post-2015 Sustainable Development Goal projects says Joshua Salomon and colleagues.

With the skyrocketing costs of modern health care, many health policy planners turn to cost effective analysis (CEA) or cost benefit analysis (CBA) to get quantitative answers for appropriateness of health procedures. This article analyzes how well approaches like CEA or CBA handle the hidden ethical judgements for such problems as: alternative treatments for an identical goal, the most effec...