BACKGROUND Escape mutations potentially allow viruses to avoid detection and clearance by the host immune system and may represent a mechanism through which infections may persist in some patients. The association of the mutations in the HBcAg gene with Hepatitis B asymptomatic carriers (ASC) has not been studied adequately. The current study was aimed to investigate HBcAg18-27 CTL epitope muta...

BACKGROUND Infectious diseases are major public health problems, among which blood-borne ones are the most important infections. Patients who undergo orthopedic surgery are at higher risk of transmitting infectious diseases from and to others, due to repeated blood examinations and injection, drains secretion and receiving blood products. Accordingly, in this study we determined prevalence of H...

OBJECTIVES To assess the prevalence of HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and co-infections among injecting drug users (IDUs) in Tehran. METHODS A sample of 899 IDUs (861 male and 38 female) was recruited in Tehran from treatment and harm reduction facilities and from drug user hangouts in public areas in equal proportions. ELISA testing for HIV, HCV antibody ...

results patients’ age ranged from 15 to 65 years (mean = 35.54 ± 14.85). thirty four (1.0%) of the subjects were positive for hbsag, of whom, 2.9 % (1 of 34 cases) were also positive in pcr-based screening. elisa tests for hbeag, hbeab, and hbcab igm were positive in one (2.9 %), 27 (79.4%) and one (2.9 %) cases, respectively. conclusions according to our results, hbsag was positive in 0.53 of ...

* Corresponding author at: Mohammad Rostami Nejad. Research Centers for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122432518, Fax: +98-2122432517. Email: [email protected] DOI: 10.5812/kowsar.1735143X.761 Copyright c 2011, BRCGL, Published by Kowsar M.P.Co. All rights reserved. c 2011 Kowsar M.P.Co. All rights reserved. Pl...

CONTEXT Hepatitis B Virus expanded program on immunization (EPI) started on 1993 in Iran. Most surveys have assessed the level of response to vaccine by measuring the titers of anti-HBs. This meta- analysis aimed to summarize the Iranian published data on the rate of vaccine-responders versus non-responders. Moreover, the impact of variables such as age, gender, type of vaccine, etc. on the lev...

Background and Objective: Since the distribution of HBV genotypes in patients with hepatitis B indicates the predominant genotypes in specific geographical area, this study aimed to investigate the prevalence of S gene mutations in high-risk children with maternal HBV in southeastern Iran. Materials and Methods: This cross-sectional prospective study was performed from March 2019 to March 2020...

background diagnosis and control programs for infectious diseases among immigrants are the most important aspects of epidemiological studies for both origin and destination countries. data about hepatitis b virus (hbv) infection among the afghan immigrants in iran is limited. objectives to the best of hbv treatment and prevention in afghan immigrants in iran, the present study was conducted to ...

BACKGROUND Occult hepatitis B infection (OBI) is a major public health problem worldwide, which harbors potential risk of hepatitis B virus (HBV) transmission through blood transfusion and transplantation. OBI is characterized by the presence of HBV-DNA in the blood or liver tissue without detectable hepatitis B surface antigen (HBsAg) in the serum. An important cause of OBI is the occurrence o...

Background: The household transmission of hepatitis B virus (HBV) is a major health problem. High incidence of HBV infection is observed within the household contacts of HBV carriers. We aimed to evaluate serological markers of hepatitis B infection among family members of HBV carriers in Arak, central Iran. Methods<stron...