It has been shown that inhaled particulate matter such as air pollution and asbestos are linked to a number of immune diseases such as asthma, and Systemic Lupus Erythematosus (SLE), respectively. This research may contribute to understanding the mechanisms of how asbestos and air pollution particulate (PM10) produce oxidative stress on macrophages, as well as how the macrophages will respond t...

Suicide is a serious public health issue worldwide, with multiple risk factors, such as severe mental illness, alcohol abuse, a painful loss, exposure to violence, or social isolation. Environmental factors, particularly chemical and meteorological variables, have been examined as risk factors for suicide, but less evidence is available on whether air pollution is related to suicide. In this is...

Air pollution consists of both gaseous and particulate-matter pollutants. The former include nitrogen dioxide (NO2), ozone (O3), and sulphur dioxide (SO2). The latter consist of particulate matter of varying aerodynamic diameter, as defined by cutoff points—for example, particles with diameters of ,10 mm (PM10) or ,2.5 mm (PM2.5). Because of their small size, these particles can be inhaled deep...

Exposure to air pollution is associated with increased cardiovascular risk but the mechanisms are poorly understood. The aim of this investigation was to assess the effect, in rats, of intratracheal instillation of particulate air pollution on leucocyte activation and damage to the vascular endothelium. Rats were exposed to particulate air pollution by intratracheal instillation of PM10. Blood ...

1.1 Ambient air pollution Uncontrolled dispersion of engineered nanoparticles may affect human health, similarly to what has been found for exposure to particles in ambient air. Particulates (in contrast to gases) are suspected to be the major factor driving the adverse effects of e.g. traffic air pollution. Human exposure to ultrafine particles in the ambient air has been associated with adver...

The detrimental effects of air pollution on health have been recognized for most of the last century. Effective legislation has led to a change in the nature of the air pollutants in outdoor air in developed countries, while combustion of raw fuels in the indoor environment remains a major health hazard in developing countries. The mechanisms of how these pollutants exert their effects are like...

This study aimed to determine if naturally occurring episodes of ozone air pollution in the Salt Lake Valley in Utah, USA, during the summer are associated with increased pulmonary inflammation and oxidative stress, increased respiratory symptoms, and decreased lung function in individuals with chronic obstructive pulmonary disease (COPD) compared to controls. We measured biomarkers (nitrite/ni...