The pattern of in vivo uptake of albendazole (ABZ) and its major metabolite, ABZ-sulphoxide (ABZSO), by Haemonchus contortus and Fasciola hepatica recovered from ABZ-treated sheep, was investigated. Concentration profiles of both compounds were simultaneously measured in target tissues/fluids from the same infected sheep. In addition, the proportion of the (+) and (-) ABZSO enantiomers was dete...

In this report, β-tubulin gene polymorphism was investigated in Haemonchus contortus  populations isolated from sheep flocks in different regions of Khouzestan province, southwestern Iran. The samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. Our objective was to study the relationship between treatment background andβ -tubulin gene po...

The effects of increased dietary protein on the performance of West African Dwarf (WAD) goats infected with Haemonchus contortus were investigated. 28 pubertal 9-12-month-old female goats were divided into two equal groups A and B and fed on high and low protein diets, respectively, from day 1 of pregnancy (day of mating) to 6 weeks post-partum. Each animal was trickle infected with a total of ...

A study was conducted to examine the duration of anthelmintic effect of copper oxide wire particles (COWP) in grazing goats, as data for the persistence of efficacy of COWP in this host species is limited. Forty-eight indigenous male goats were infected naturally by grazing them on Haemonchus contortus-infected pasture. When the faecal egg count (FEC) in the goats was 3179 ± 540 eggs per gram o...

AIM The effects of N-P-K fertilizers in the form of urea, single super phosphate and muriate of potash on development of free-living stages of Haemonchus contortus were studied. MATERIALS AND METHODS Five parasite free experimental plots of 1 m×1 m area, each of paddy leaves (15-day-old) and an equal number of Cynodon dactylon grass were infested with about 10×104 eggs/ml phosphate buffer sal...

The anthelmintic effect of acetone leaf extract and fractions of Anogeissus leiocarpus was investigated to determine the relative efficacy of the components as anthelmintic against Haemonchus contortus (Rudolphi). The fractions were obtained by solvent-solvent group separation of the leaf extract. The fractions were evaluated for ovicidal and larvicidal activity by egg hatch inhibition assay an...

Following claims of anthelmintic activity of Cereus jamacaru DC (Cactaceae) by a commercial farmer, in vivo studies were conducted to determine the possible direct anthelmintic effects of the plant on ovine gastrointestinal nematodes. Eighteen sheep were infected with 4000 Haemonchus contortus and 6000 Trichostrongylus colubriformis larvae given in three divided doses over a period of three day...

Two doses of infective larvae of 20 000 Trichostrongylus axei, dosed to Merino lambs at an interval of 14 days and subsequently challenged with Ostertagia circumcincta, caused a significant reduction (P less than 0.01) in the establishment of 5th and adult stages of the latter. T. axei was unable to protect Merino sheep against homologous challenge nor was Haemonchus contortus a successful vacc...

The purpose of this study was to evaluate the predatory activity of the nematode Butlerius spp. and fungal isolates of Duddingtonia flagrans, Clonostachys rosea, Arthrobotrys musiformis and Trichoderma esau against H. contortus infective larvae (L3) in grass pots. Forty-eight plastic gardening pots containing 140 g of sterile soil were used. Panicum spp. grass seeds (200 mg) were sown into each...