Rheumatoid arthritis (RA) is found more often in subjects carrying the HLA-DR1 antigen and some subtypes of the HLA-DR4 antigen than in those without these antigens. Analysis of probes specific for HLA-DR4 has shown that amino acids encoding positions 69-74 (EQRRAA) of the beta chain indicates susceptibility to RA. A hexamer sequence of proteus haemolysin spanning residues 32-37 (ESRRAL) has be...

The coincidence of virulence factors such as haemolysin, adhesins and 0 · and K antigens among strains of Escherichia coli causing urinary tract infections (UTI) is well-documented.-4 lndeed it seems that prominent uropathogenic strains belang to a restricted number of clonal types possessing specific constellations of these chromosomally-encoded characters and that such associations frequently...

Background: Candida species is a normal commensal flora of human body inhabiting the skin, mucous membrane and gastro intestinal tract but may be associated with superficial deep-seated fungal infections. The switch from to potent pathogen, facilitated by various extracellular hydrolytic enzymes. aim this study was estimate phospholipase, proteinase, haemolysin esterase activity determine antif...

urinary tract infections (utis) are significant health problem, with escherichia coli as the primary pathogen in proximally 80% of cases. the adhesion of e coli to the host cell can be influenced by cell surface hydrophobicity (csh) and is an important factor for the development of infections. this study was conducted to find the relation between csh and one of the adhesions (mannose resistant ...

Haemolysins of Salmonella are important due to their probable role in pathogenesis of systemic salmonellosis and use in sub-serovar level typing. The present study was undertaken to determine haemolytic potential of Salmonella Gallinarum strains through phenotypic and genotypic methods. Amplification of haemolysin gene (clyA) and cytolysin gene (slyA) was attempted in order to determine their r...

The ATPase activity of the ABC (ATP-binding cassette) ATPase domain of the HlyB (haemolysin B) transporter is required for secretion of Escherichia coli haemolysin via the type I pathway. Although ABC transporters are generally presumed to function as dimers, the precise role of dimerization remains unclear. In the present study, we have analysed the HlyB ABC domain, purified separately from th...