OBJECTIVE To investigate the effect of immunosuppressive anticancer therapy on titre levels of anti-hepatitis B surface antibodies (anti-HBs) in hepatitis B surface antigen (HBsAg) negative and anti-HBs positive patients with haematological malignancies or solid tumours. METHODS This retrospective study reviewed the medical records of patients with haematological malignancies or solid tumours...

OBJECTIVES Knowledge of health related quality of life of haematological patients is limited. This study aimed at investigating the prevalence and predictors of symptoms and problems in a representative sample of haematological patients in Denmark. METHODS A random sample of patients with leukaemia, multiple myeloma and advanced lymphoma (n = 732) received the European Organisation for Resear...

Although iron overload is clinically significant, only limited data have been published on iron overload in haematological diseases. We investigated cardiac and liver iron accumulation by magnetic resonance imaging (MRI) in a cohort of 87 subjects who did not receive chelation, including 59 haematological patients. M-HIC (MRI-based hepatic iron concentration, normal values <36 μmol/g) is a non-...

OBJECTIVE While iron deficiency is regarded as the major cause of nutritional anaemia, changes in vitamins A, B12, C and E, folic acid and riboflavin status have also been linked to its development and control. This paper provides a systematic review of vitamin supplementation trials relating to the control of nutritional anaemia. METHODS A MEDLINE search was used to find reports of vitamin s...

BACKGROUND Establishment of haematological and biochemical reference intervals is important to assess health of animals on individual and population level. Reference intervals for 13 haematological and 34 biochemical variables were established based on 88 apparently healthy free-ranging brown bears (39 males and 49 females) in Sweden. The animals were chemically immobilised by darting from a he...

BACKGROUND Urogenital schistosomiasis is a widely contracted parasitic helminth infection often associated with haematological abnormalities. AIM We investigated the relationship between the haematological profile and the intensity of schistosomiasis among children in the Yeji district. MATERIALS AND METHODS A total of 100 participants comprising 50 Schistosoma haematobium (S. haematobium) ...

BACKGROUND Several models for mortality prediction have been constructed for critically ill patients with haematological malignancies in recent years. These models have proven to be equally or more accurate in predicting hospital mortality in patients with haematological malignancies than ICU severity of illness scores such as the APACHE II or SAPS II 1. The objective of this study is to compar...

Haematological neoplasms comprise a collection of heterogeneous neoplastic conditions that arise from cells the bone marrow and lymphoid system. This study describes pattern distribution haematological at tertiary hospital inNorthernProvince,Sri Lanka. A descriptive retrospective audit was conducted ofall diagnosed by peripheral blood examination. total 435 were reported during 4-year period. A...

BACKGROUND Bone marrow examination is regarded as one of the most important diagnostic procedure to assess various haematological disorders. The uses and advantages of bone marrow aspiration are numerous. This study was conducted with the aim to evaluate the frequency of involvement of bone marrow with malignant and non-malignant haematological and other clinical disorders and to observe the si...

BACKGROUND Persistent hyperglycaemia is a hallmark of Diabetes Mellitus (DM). It causes increased production of free radicals, especially reactive oxygen species (ROS), - resulting in oxidative stress. Reactive Oxygen Species have been implicated in the development of haematological complications in patients with diabetes. Superoxide Dismutase (SOD) is one of the most effective antioxidant enzy...