نتایج جستجو برای: h5 index

تعداد نتایج: 398069  

Journal: :Molecular pharmacology 2009
Nicole Toohey Michael T Klein Jessica Knight Carol Smith Milt Teitler

We have previously reported on the unusual human 5-hydroxytryptamine(7) (h5-HT(7)) receptor-inactivating properties of risperidone, 9-OH-risperidone, bromocriptine, methiothepin, metergoline, and lisuride. Inactivation was defined as the inability of 10 microM 5-HT to stimulate cAMP accumulation after brief exposure and thorough removal of the drugs from HEK293 cells expressing h5-HT(7) recepto...

2013
Valérie Vierstraete

The human development index (HDI) is a measure of development which allows countries’ development to be assessed on the basis of three indicators that measure the health, education, and standard of living of the population. The UNDP also computes a human development index that excludes this last indicator, the non-income HDI. The HDI, like the non-income HDI, presents some striking intercountry...

Journal: :The Onderstepoort journal of veterinary research 2008
C Abolnik

A Fluorescence resonance energy transfer (FRET) real-time reverse-transcription (rRT-PCR) assay was developed that distinguishes stains of South African and European highly pathogenic (HPAI) from low pathogenicity (LPAI) H5 avian influenza viruses in the absence of virus isolation, irrespective of the length of insertion at the hemagglutinin cleavage site (H0). The assay was used to pathotype H...

Journal: :The Journal of pharmacology and experimental therapeutics 2012
Mark J Millan Clotilde Mannoury la Cour Benjamin Chanrion Delphine S Dupuis Benjamin Di Cara Valérie Audinot Didier Cussac Adrian Newman-Tancredi Maud Kamal Jean A Boutin Ralf Jockers Philippe Marin Joël Bockaert Olivier Muller Anne Dekeyne Gilbert Lavielle

Although most antidepressants suppress serotonin (5-HT) and/or noradrenaline reuptake, blockade of 5-HT(2C) receptors and α(2)-adrenoceptors likewise enhances monoaminergic transmission. These sites are targeted by the urea derivative N- [4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-1,2-dihydro-3-H-benzo[e]indole-3-carboxamide (S32212). S32212 was devoid of affinity for monoamine reuptake sites,...

2018
Jinping Li Guangyu Hou Yan Wang Suchun Wang Cheng Peng Xiaohui Yu Wenming Jiang

Citation: Li J, Hou G, Wang Y, Wang S, Peng C, Yu X and Jiang W (2018) Influenza Viral Vectors Expressing Two Kinds of HA Proteins as Bivalent Vaccine Against Highly Pathogenic Avian Influenza Viruses of Clade 2.3.4.4 H5 and H7N9. Front. Microbiol. 9:604. doi: 10.3389/fmicb.2018.00604 Influenza Viral Vectors Expressing Two Kinds of HA Proteins as Bivalent Vaccine Against Highly Pathogenic Avian...

2017
Hye Kwon Kim Dae Gwin Jeong Sun-Woo Yoon

Outbreaks of H5 highly pathogenic avian influenza viruses (HPAIVs) have caused economic loss for the poultry industry and posed a threat to public health. In South Korea, novel reassortants of HPAIVs such as H5N6 and H5N8 had been circulating in poultry. Here, we will discuss the identity of recent novel reassortants of Korean H5 HPAIVs and the recent advances in vaccine development, which will...

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