The complex and ancient relationships between animal hosts and the microbial communities that inhabit their digestive tracts have become the focus of intense research in recent years. As a result, our understanding of gut microbial ecology and of the evolutionary and physiologic impacts of gut microbial communities in animal hosts has grown markedly. Indeed, members of the gut microbiota have n...

The gut microbiome is a complex ecosystem that affects the development, immunological responses and nutritional status of the host. Efforts are being made to unravel the complex interaction between the gut microbiome and host to have a greater understanding about its role in human health. Colonization of the gut by microbes begins at birth, but the succession and composition of the microbial co...

Gut microbiota is a collection of microbial organisms that naturally exist within the gastrointestinal (GI) tract. It is clear that the gut microbiota is involved in host physiological development, defense against pathogens and diseases. Thus, gut microbiota is regarded as a hidden organ composed of other kinds (Bocci, 1992). A feature of the gut microbiota is that the compositional microbes ar...

Whereas both ethanol and gut ischemia/reperfusion (I/R) are known to alter hepatic microvascular function, little is known about the influence of ethanol consumption on the hepatic microvascular responses to I/R. The objective of this study was to determine whether acute ethanol administration exacerbates the hepatic microvascular dysfunction induced by gut I/R. Rats were exposed to gut ischemi...

The growth rate of the pig is most rapid during the neonatal and weaning periods. Nutrition and gastrointestinal function play a critical role in the survival, health and growth of the young pig during this transition from suckling to weaning. The high metabolic rate and cellular turnover of gut tissues result in substantial fi rst-pass utilization of dietary nutrients, especially amino acids, ...

Compartmental differences in human immunodeficiency virus type 1 (HIV-1) between the gut and peripheral blood and within the gut were examined. Biopsy specimens from the colon and ileum and peripheral blood samples were collected from chronically HIV-1-infected individuals. HIV-1 envelope sequences were examined from cell-associated DNA and RNA and virion RNA. Phylogenetic analysis revealed no ...

Recent findings have demonstrated that the gut microbiome complements our human genome with at least 100-fold more genes. In contrast to our Homo sapiens-derived genes, the microbiome is much more plastic, and its composition changes with age and diet, among other factors. An altered gut microbiota has been associated with several diseases, including obesity and diabetes, but the mechanisms inv...

Microbiota is a set of microorganisms resident in gut ecosystem that reacts to psychological stressful stimuli, and is involved in depressed or anxious status in both animals and human being. Interestingly, a series of studies have shown the effects of physical exercise on gut microbiota dynamics, suggesting that gut microbiota regulation might act as one mediator for the effects of exercise on...

Every single human consists of thousands of genes, billions of neurons and trillions of bacteria. There is a rapidly growing number of data that links the gut microbiome to the development and functioning of the central nervous system, which is a currently proposed paradigm shift in neuroscience. Knowledge on the relationship between gut microbiota and mental disorders is constantly increasing....

The mechanisms underlying gut development, especially peristalsis, are widely studied topics. However, the causes of gut peristalsis-related diseases, especially Opioid-Induced Bowel Dysfunction (OIBD) disorder, have not been well defined. Therefore, our study used zebrafish, a popular model for studying both gut development and peristalsis, and DCFH-DA, a dye that clearly labels the live fish ...