This review describes the application of 2 nuclear imaging techniques for assessment of hepatic function in the setting of liver surgery and transplantation. The biochemical and technical background, as well as the clinical applications, of (99m)Tc-labeled diethylenetriaminepentaacetic acid galactosyl human serum albumin (GSA) scintigraphy and hepatobiliary scintigraphy (HBS) with (99m)Tc-label...

The objective of this study was to investigate clinical utility of a graphical method for estimating liver uptake and blood retention of 99mTc-DTPA-galactosyl human serum albumin (99mTc-GSA; DTPA is diethylenetriaminepentaacetic acid) using dynamic single photon emission computed tomography (SPECT) data. When considering the kinetics of 99mTc-GSA, if it is assumed that (1) 99mTc-GSA distributes...

In Alzheimer's disease (AD), structural and functional brain network organization is disturbed. However, many of the present network analysis measures require a priori assumptions and methodological choices that influence outcomes and interpretations. Graph spectral analysis (GSA) is a more direct algebraic method that describes network properties, which might lead to more reliable results. In ...

In this paper, a hybrid gravitational search algorithm (GSA) and pattern search (PS) technique is proposed for load frequency control (LFC) of multi-area power system. Initially, various conventional error criterions are considered, the PI controller parameters for a two-area power system are optimized employing GSA and the effect of objective function on system performance is analyzed. Then GS...

doi: 10.1130/G32869.1 2012;40;407-410 Geology Naish, Benjamin S. Cramer, Yair Rosenthal, W. Richard Peltier and Sindia Sosdian Kenneth G. Miller, James D. Wright, James V. Browning, Andrew Kulpecz, Michelle Kominz, Tim R. deglaciation High tide of the warm Pliocene: Implications of global sea level for Antarctic Email alerting services articles cite this article to receive free e-mail alerts wh...

The heap leaching of minerals is one of the more commonly used processes in the mining industry. This process has been modeled by many authors. However, the validation, verification, and implementation of these models are difficult since there is uncertainty about the operating conditions and the leaching model parameters. This work uses the uncertainty quantification, based on uncertainty and ...

Complex optimization problems that cannot be solved using exhaustive search require efficient search metaheuristics to find optimal solutions. In practice, metaheuristics suffer from various types of search bias, the understanding of which is of crucial importance, as it directly pertinent to the problem of making the best possible selection of solvers. Two metrics are introduced in this study:...

In this study we analyzed the influence of region of interest (ROI) selection on the uptake ratio of the liver to the liver plus heart at 15 min (LHL15) during (99m)Tc-galactosyl human serum albumin (GSA) scintigraphy and determined the optimal ROI by evaluating the individual effects of different ROIs in the heart on LHL15. Twenty patients were randomly selected from those who had undergone (9...

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MOTIVATION Group-wise pattern analysis of genes, known as gene-set analysis (GSA), addresses the differential expression pattern of biologically pre-defined gene sets. GSA exhibits high statistical power and has revealed many novel biological processes associated with specific phenotypes. In most cases, however, GSA relies on the invalid assumption that the members of each gene set are sampled ...