BACKGROUND We compared the outcomes in propensity score-matched high-risk patients (European System for Cardiac Operative Risk Evaluation [EuroSCORE] ≥ 5) undergoing off-pump coronary artery bypass graft surgery using bilateral or single skeletonized internal thoracic artery (ITA). METHODS AND RESULTS Of 794 consecutive patients undergoing isolated coronary artery bypass graft surgery (788 by...

Hypercoagulability has been reported after off-pump coronary artery bypass grafting (OPCAB) compared with patients undergoing standard coronary artery bypass grafting (CABG) with cardiopulmonary bypass. The aim of this study was to evaluate the changes in platelet reactivity in response to cardiac surgery, both OPCAB and CABG. Platelet reactivity was monitored pre- and postoperatively (days 1 a...

Background: A non-invasive continuous measurement of hemoglobin (Hb) by pulse co-oximetry (SpHb) using Radical-7® (Masimo Corporation, CA, USA) is a newly developed method of measuring total Hb concentration. Previously, the accuracy of SpHb in clinical settings was reported (1). However, it has been also reported that SpHb has poor correlation with arterial Hb after cardiac surgery (2). Here w...

BACKGROUND Despite continuous improvements in materials and perfusion techniques, cardiac surgery still causes lung injury and a delay of pulmonary recovery. Currently, there is no gold standard for quantifying cardiac surgery induced lung injury and dysfunction. Adding objective measures, such as plasma biomarkers, could be of great use here. In this study the utility of lung epithelium specif...

Advances in technology, the desire to minimize blood product transfusions, and concerns relating to inflammatory mediators have lead many practitioners and manufacturers to minimize cardiopulmonary bypass (CBP) circuit designs. The oxygenator and arterial line filter (ALF) have been integrated into one device as a method of attaining a reduction in prime volume and surface area. The instruction...

Background—We compared the outcomes in propensity score-matched high-risk patients (European System for Cardiac Operative Risk Evaluation [EuroSCORE] 5) undergoing off-pump coronary artery bypass graft surgery using bilateral or single skeletonized internal thoracic artery (ITA). Methods and Results—Of 794 consecutive patients undergoing isolated coronary artery bypass graft surgery (788 by the...

BACKGROUND The brain-derived protein S100B has been shown to be a useful marker of brain injury of different etiologies. Cognitive dysfunction after cardiac surgery using cardiopulmonary bypass has been reported to occur in up to 70% of patients. In this study we tried to evaluate S100B as a marker for cognitive dysfunction after coronary bypass surgery with cardiopulmonary bypass in a model wh...

This study aims to demonstrate the use of surgical ostioplasty left main coronary artery as an alternative technique conventional bypass grafting for treatment stem-isolated ostial stenosis. From 2002 2021, five patients—three women (60%) and two men (40%)—presented with a history angina pectoris were diagnosed isolated stenosis ostia associated normal distal arteries. Pre-operative cardiac cat...

AIM Recently minimally invasive direct coronary artery bypass grafting (MIDCAB) has become an interesting alternative to conventional coronary artery bypass grafting, especially in patients with a high-grade left anterior descending coronary artery (LAD) stenosis unsuitable for balloon angioplasty. Although MIDCAB offers several advantages such as the avoidance of sternotomy and cardiopulmonary...

OBJECTIVE The authors performed a retrospective cost analysis for patients undergoing revascularization of their left anterior descending (LAD) coronary artery either by standard coronary artery bypass grafting (CABG), percutaneous transluminal coronary angioplasty (PTCA), or minimally invasive coronary artery bypass grafting (MICABG). SUMMARY BACKGROUND DATA Minimally invasive CABG has becom...