Alternatives to autogenous bone graft for spinal fusion have been investigated for many years. It has been shown that osteoconductive materials alone do not give a rate of fusion which is comparable to that of autogenous bone graft. We analysed the effectiveness of porous ceramic loaded with cultured mesenchymal stem cells as a new graft material for spinal fusion in an animal model. Posterolat...

STUDY DESIGN This is an experimental animal study. OBJECTIVE The objective of this study was to compare an anterior cervical discectomy and interbody fusion of a novel polylactide/nano-sized β-tricalcium phosphate (PLA/nβ-TCP) bioabsorbable self-retaining cervical fusion cage (BCFC) with an autologous bone graft and polyetheretherketone (PEEK) cages. BACKGROUND Although PLA cervical cages h...

In 1878, Emil Berthold was the first to describe the surgical procedure of myringoplasty, using a free skin graft from the forearm,1 although Edward Ely argued in a later publication that he had been the pioneer in this procedure.2 But it was only in the 1950s that tympanoplasty-related articles reappeared in the literature. The fundamental principles of the surgical procedure were described by...

Treatment of congenital heart defects in children requiring right ventricular outflow tract reconstruction typically involves multiple open-heart surgeries because all existing graft materials have no growth potential. Here we present an 'off-the-shelf' vascular graft grown from donor fibroblasts in a fibrin gel to address this critical unmet need. In a proof-of-concept study, the decellularize...

A new synthesis of bis(acyl)phosphane oxide (BAPO) photoinitiators was developed which can be used to functionalize cellulose nanocrystal surfaces for polymer grafting. Hybrid materials with excellent graft yields can be rapidly obtained under mild and acid-free conditions.

The author prefers autologous tissue from a combined SMAS/fat graft for lip augmentation. However, he considers Alloderm the best alternative. Here he describes his technique and compares Alloderm with other available materials.

Acrylic bone cement has considerable laboratory and clinical data validating it as a delivery material for depot administration of antibiotics. However, an alternate material that does not require a secondary procedure for removal is desired. Many biodegradable materials have been evaluated as alternatives including protein-based materials (collagen, fibrin, thrombin, clotted blood), bone-graft...

BACKGROUND The aim of the study was to investigate the in vivo efficacy of local and systemic antibiotic prophylaxis in the prevention of Staphylococcus (S.) epidermidis graft infection in a rat model and to evaluate the bacterial adherence to frequently used prosthetic graft materials. METHODS Graft infections were established in the subcutaneous tissue of 120 male Wistar rats by implantatio...

PURPOSE Artificial grafts have been investigated for use in the repair of oral mucosal defects. The aim of this retrospective study was to present the outcomes of the use of acellular dermal matrix (ADM) grafts to repair oral mucosal defects. MATERIALS AND METHODS Data from 36 patients with oral mucosal defects reconstructed with ADM grafts from 2003 through 2009 were reviewed. All patients w...

AIM Fat graft migration following spinal cord surgery is an uncommon problem. Only few cases of fat graft migration causing cauda equine syndrome, recurrent sciatica, and root compression following lumbar spine surgery have been reported. We report a case of fat graft migration causing symptomatic cervical cord compression. MATERIAL AND METHODS A 45-years-old male with cervica...