نتایج جستجو برای: gonadectomy
تعداد نتایج: 609 فیلتر نتایج به سال:
Introduction: Sex differences are observed in the development of tolerance to antinociceptive effect of opioid drugs such as morphine, but the underlying mechanisms remain unclear. Critical role of glutamate in the development and maintenance of opioid tolerance has been reported by many investigators. There are also evidences about interaction between gonadal hormones and neuromodulatory sy...
the previous studies have been suggested that to tolerance,sensitivity and pain threshold are different between men and women.these differences can be affected by various factors.in this study,the effect of gonadectomy on gender differences in thermal pain sense threshold was tested hot plate method in rats.therefore the reaction time(the delay occurred in response to thermal stimulus)at zero,1...
Agouti-related peptide (AgRP), the endogenous antagonist to the melanocortin 3 and 4 receptors, elicits robust hyperphagia and weight gain in rodents when administered directly into the central nervous system. The relative influence of AgRP to cause weight gain in rodents partially depends on the activity level of the melanocortin agonist-producing proopiomelanocortin neurons. Both proopiomelan...
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