The use of urinary and/or biliary excretion data was considered as an alternative approach if the bioanalytical method lacked the appropriate sensitivity to adequately characterize the serum or plasma concentration-time profile. This approach is used for the analysis of plasma concentration-time profile under the lower limit of quantification (LLOQ) of various analytical instruments. The object...

Changes in the transport parameters and the chemical nature of the surface of composite polyamide/polysulfone membranes due to both aging and treatment with chemical products (HCl, H(3)NO, and NaOH) have been considered. Hydraulic and salt permeability were obtained from water flow and salt diffusion measurements, respectively, and their values seem to indicate a modification in the structural ...

Electron paramagnetic resonance (EPR), Fourier transform infrared (FTIR), and solid-state 15N nuclear magnetic resonance (15N-NMR) spectroscopies were used to characterize the structure and relative strength of the interactions between metal sulfonate and amide groups in blends of lightly sulfonated polystyrene ionomers and an N-methylated polyamide, poly(N,N′-dimethylethylene sebacamide), and ...

Enzymes are powerful tools in organic synthesis that are able to catalyse a wide variety of selective chemical transformations under mild and environmentally friendly conditions. Enzymes such as the lipases have also found applications in the synthesis and degradation of polymeric materials. However, the use of these natural catalysts in the synthesis and the post-synthetic modification of dend...

Mirroring of missing facial parts and rapid prototyping of templates have become widely used in the manufacture of prostheses. However, mirroring is not applicable for central facial defects, and the manufacture of a template still requires labour-intensive transformation into the final facial prosthesis. We have explored innovative techniques to meet these remaining challenges. We used a morph...

Fluorescent methods for the sequence specific detection of DNA are vital to unraveling the functional, three-dimensional significance of the linear human genome. The ability of minor groove-binding polyamides to specifically target predetermined DNA sequences, without sample denaturation, in biologically relevant condensed states and protein complexes, offers appreciable advantages relative to ...

Linked polyamides bind in the minor groove of double-stranded DNA in a partially sequence-specific manner. This report analyzes the theoretical limits of DNA sequence discrimination by linked polyamides composed of two to four different types of heterocyclic rings, determining (i) the optimal choice of base-binding specificity for each ring and (ii) the optimal design for a polyamide composed o...

• Microalgae harvesting is a major bottleneck to microalgae-based biofuel production. Flocculation the most versatile, energy-efficient and cost-efficient process. Polyacrylamides exhibit high performance at different operation scales. Comprehensive analysis of polyacrylamide-microalgae flocculation was presented. Properties polyacrylamide microalgae culture influence biomass touted as highly p...

Means to cause an immunogenic cell death could lead to significant insight into how cancer escapes immune control. In this study, we screened a library of five pyrrole-imidazole polyamides coding for different DNA sequences in a model of B-cell lymphoma for the upregulation of surface calreticulin, a pro-phagocytosis signal implicated in immunogenic cell death. We found that hairpin polyamide 1...

this study was conducted to evaluate the effect of high co2 modified atmosphere packaging (map) on storage quality of ‘selva’ strawberry fruits. the statistical analysis carried out using factorial experiment by completely randomized design (crd) with three replications. treatments included cover in two levels (polyethylene and polyamide) and two different gas compositions (2% o2 + 15% co2 + 83...