We have characterized a new selenium-dependent glutathione peroxidase, GSHPx-GI, by expressing a GSHPx-GI cDNA isolated from human hepatoma HepG2 cells in human mammary carcinoma MCF-7 cells, which have virtually undetectable expression of either the classical cellular enzyme, GSHPx-1, or GSHPx-GI at the protein level. One of the G418-resistant clones, neo-D1, expresses the transfected GSHPx-GI...

The cerebral ischemia in rats was induced by occluding bilateral common carotid arteries (BCCAO) for 30 min., followed by 45 min reperfusion. BCCAO caused significant depletion in superoxide dismutase, catalase, glutathione, glutathione peroxidase, glutathione-S-transferase, glutathione reductase and significant increase in lipid peroxidation along with severe neuronal damage in the brain. All ...

The purpose of the current study was to determine possible improvement in soybean plants’ tolerance against vanadium-induced stress response application olive solid waste (OSW) and selenium nanoparticles (Se-NPs), by assessing metabolites plant defense systems. Drawing upon this aim, a pot experiment performed where plants were grown with fertilization treatment (including, control, OSW, Se-NPs...

Erectile dysfunction (ED) drugs have been used for treatment of erectile dysfunction which affects the lives of approximately 300 million men worldwide. It is well known that the cytosolic glutathione Stransferase (GST) and glutathione metabolizing enzymes play an important role in the detoxification of many endogenous and exogenous compounds. Therefore, the present study aims at investigating ...

The goal of this work was the research chondroitin sulfate prophylactic action on glutathione system state in rat blood serum during acute joint inflammation. performed white non-linear pubertal males weighting 160-240 grams compliance to all general ethical principles animal research. All animals were divided four experimental groups. first group – control: injected with 0,1 ml 0,9 % NaCl solu...