Concurrieron a la ceremonia diversas personalidades en representación de la Academia Nacional de Ciencias, la Academia Nacional de Medicina, la Academia Peruana de Salud, la Academia Peruana de Cirugía, la Universidad Nacional Mayor de San Marcos y la Universidad Peruana Cayetano Heredia; así también, editores de revistas médico–científicas, miembros del Consejo Consultivo de la Revista, person...

Lifelong employment commitments are a relatively uncommon employment contract. We …nd that three factors can explain their existence in academia – (i) non-contractibility of output, (ii) discipline-speci…c investment by a faculty member that enhances the chance of high output within the profession but that also signi…cantly diminishes the faculty member’s outside-occupation alternatives and (ii...

One of the goals of the recent workshop, “An Eye on Glaucoma: New Opportunities for Treatment,” was to highlight areas of glaucoma research that, with appropriate funding, are ripe for major advancement for prevention, diagnosis, and treatment. Another goal was the exploration of collaborative partnership and the process for facilitating translation of these areas, not just for glaucoma but for...

Herein, we report a conceptually novel clinical case highlighting the diagnostic implications of excessive homozygosity and its correlation with brain MRI abnormalities in an infant with GA1. The case also points a need for an extra amount of caution to be exercised when evaluating patients with "negative exomes."

Treatment of the genetic metabolic myopathies remains generally unsatisfactory with the exception of a select few. Multiple Acyl Co-A Dehydrogenase Deficiency (Glutaric Aciduria type II), in particular, has been shown to respond well to riboflavin supplementation. Recently, studies have also confirmed the effectiveness of recombinant enzyme replacement therapy for Acid Maltase Deficiency (Pompe...

detected. Ii both cases malonic acid was by far the most abundant product. The traces of glutaric and adipic acid in the oxidation products of the C18 and C1,9 acid respectively, can be explained by the presence of C20 and C21 pentaenoic acid, from which the above dicarboxylic acids are the known oxidation products. However, the possible presence of small amounts of an isomeric octadecatetraeno...

Sulfone-substituted γ- and δ-lactams have been prepared in a single step with high diastereoselectivity. Sulfonylglutaric anhydrides produce intermediates that readily decarboxylate to provide δ-lactams with high diastereoselectivity. Substituents at the 3- or 4-position of the glutaric anhydride induce high levels of stereocontrol. Sulfonylsuccinic anhydrides produce intermediate carboxylic ac...