A 72-year-old woman was admitted to our hospital with abdominal pain, fever, and weight loss. Physical examination revealed tenderness in the epigastrium. Laboratory data showed a white blood cell count of 12,600 10/L (normal range, 4800-10,800 10/L) and increases in the serum levels of amylase (379 IU/L; normal <160 IU/L); aspartate aminotransferase (78 IU/L; normal 1-21 IU/L), alanine (60 IU/...

We evaluated the effects of aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) on sodium arsenite-induced hepatotoxicity in Wistar rats. We observed that treatment of the animals with the extracts before or just after sodium arsenite administration significantly (p < 0.05) reduced mean liver and serum γ-Glutamyl transferase (γGT), and serum alkaline phosphatase (ALP) activiti...

Background. Patients who underwent Fontan oper ion have some degree of liver disease. We aimed ssess the long-term liver and cardiac function a ontan operation. Methods. Patients enrolled underwent physical exam nation, biochemical tests (aspartate aminotransferas lanine aminotransferase, gamma glutamyl transpept ase, bilirubin, international normalized ratio, coagu ion factor V, protein profil...

Glutamyl-tRNA (Glu-tRNA), formed by Glu-tRNA synthetase (GluRS), is a substrate for protein biosynthesis and tetrapyrrole formation by the C(5) pathway. In this route Glu-tRNA is transformed to delta-aminolevulinic acid, the universal precursor of tetrapyrroles (e.g., heme and chlorophyll) by the action of Glu-tRNA reductase (GluTR) and glutamate semialdehyde aminotransferase. GluTR is a target...

The present study investigated the effects of Bifidobacterium longum BB536 on lipid profile, liver and kidney function, and body fat in hypercholesterolaemic rats. 40 Sprague-Dawley rats were randomly divided into five groups. The negative control group received a standard diet. The positive control group received a cholesterol-enriched diet, whereas the intervention groups received a cholester...

Alanine aminotransferase (ALT), gamma-glutamyl-transferase and hepatitis B core antibodies were evaluated as donor markers in a prospective study of 685 open-heart surgery patients. Of these three surrogate markers, only an ALT level greater than or equal to 2 SD above the log mean had a significant association with recipient non-A, non-B hepatitis (NANBH, p = 0.02). Antibodies to the hepatitis...

&#x0D; Aims: Several parts of medicinal plants have been known to many health benefits. One those is the Crinum glaucum (CG) bulb. Therefore, this research was undertaken investigate therapeutic role an aqueous extract CG bulb (aeCGb) against lipopolysaccharide (LPS)-induced haematological and hepatic enzyme alterations in male female rat models.&#x0D; Study Design Methodology: Twenty-five twen...

Acetaminophen (N-acetyl-p-aminophenol, APAP) is the most popular drug recommended and consumed for relieving mild moderate pain fever. Although effective in therapeutic doses, APAP overdose induces hepatotoxicity, causing acute liver failure. In this study, hepatoprotective effects underlying mechanisms of Lavandula officinalis essential oil (LEO) were investigated APAP-induced hepatotoxicity. ...

The present study was conducted to determine the hematobiochemical analysis of ostrich (Struthio camelus) with respect gender and progressive age. A total 40 apparently healthy ostriches both genders two age groups; young one (1 year 2.4 years: group A); adult (2.5 years 5 B) in equal number were used this study. Blood samples collected from wing vein maintained farms near Gogra Pakistan. For h...

Background: Hepatotoxicity is one of the most important side effects anticonvulsant drugs. This study compared hepatotoxicity sodium valproate, carbamazepine, phenytoin, lamotrigine, and vigabatrin in male rats. Methods: Based on results, 56 rats were randomly divided into seven groups eight treated intraperitoneally for four weeks. Groups 1 2 received 500 mg/kg carbamazepine 3, 4, 5 injected w...