Optical and medical devices require microdrilling of holes on glass. Brittle fracture occurs during the drilling. Cone and radial cracks are generated due to impact load and walking when a drill hit a glass to make a hole. To produce good holes without cracks and fracture, a condition monitoring of glass drilling processes is required. In this paper, to develop a costeffective direct monitoring...

We here report a new culturing method to produce micro vascular-mimetic tissue consisting of smooth muscle cells (SMCs) and endothelial cells (ECs) toward the practical use of tissue engineering. To achieve the stable coculture, the requirements for SMC culture in microchannels are clarified by basic experiments. Then, a new microchip that satisfies those requirements was developed by bonding g...

This paper reviews ongoing progress in the design and fabrication of new, on-chip, low loss planar molecular sensors. We report the details of device design, material selection and manufacturing processes used to realise high-index-contrast (HIC), compact micro-disk resonators. These structures have been fabricated in thermally evaporated Asand Ge-based chalcogenide glass films with PDMS (polyd...

This work reports on diverse technologies implemented for fabricating microfluidic devices such as biomedical micro sensors, micro pumps, bioreactors and micro separators. UV depth lithography and soft lithography were applied in the fabrication processes using different materials, for example SU-8, polydimethylsiloxane (PDMS), silicon, glass and ceramics. Descriptions of the fabrication proces...

A living cell microarray consists of an orderly arrangement of cells attached to a solid support such as a glass microscope slide. The chief difficulty of obtaining such arrays is the fabrication of substrates patterned with micro-wells, adhesive spots, or other features to guide orderly cell attachment. Here we report a novel method using woven Nylon mesh to micropattern three-dimensional algi...

Introduction Glass Ionomer Cements (GIC) are widely used dental materials. They adhere to hard dental tissues, release fluoride ions and are bio-compatible [ 11. GIC are obtained from the reaction during the hardening process between a polymeric acid and acid-degradable glass. Water plays a crucial role in this reaction; its absence retards or prevents the reaction while high concentrations res...

Laser spectroscopy of atoms confined in vapor cells can be strongly affected by the presence of background gases. A significant source of vacuum contamination is the permeation of gases such as helium (He) through the walls of the cell. Aluminosilicate glass (ASG) is a material with a helium permeation rate that is many orders of magnitude lower than borosilicate glass, which is commonly used f...

Network science plays an increasingly important role to model complex data in many scientific disciplines. One notable feature of network organization is community structure, which refers to clusters of tightly interconnected nodes. A prominent problem is how to investigate the relationship between macro-scale modules that are retrieved by optimizing global network measures, and micro-scale str...

This paper reports a self-aligned three-dimensional process (3D-SOULE) that incorporates batch-mode micro ultrasonic machining (μUSM), lapping and micro electro-discharge machining (μEDM) for fabrication of concave and mushroom-shaped spherical structures from hard and brittle materials. To demonstrate the process, 1 mm structures are fabricated from glass and ruby spheres. The μEDM technique i...

This paper describes the work done in an attempt to integrate ultrasonic sensors in micro-fluidic channels. We have developed a system with fluidic channels having embedded zinc oxide transducers. A zinc oxide film is deposited on a glass substrate and is sandwiched between two electrodes. The transducers made are found to resonate at 400 MHz in thickness mode. The channels are made both from P...