introduction: osteoporosis and periodontal diseases are both multifactorial and are mostly associated with aging. the aim of this study was to evaluate the relationship between osteoporosis and periodontal diseases. materials and methods: in this analytical/cross-sectional study, periodontal examinations were carried out on 98 women who had undergone bone mass densitometry. of these cases, cons...

BACKGROUND Gingival overgrowth was reported as a side effect after chronic administration of several drugs, which, despite their different pharmacological effect, seem to have the gingival mucosa as a secondary target. The thickness of the gingival epithelium and fibrosis in the lamina propria are unspecific changes that together determine the enlargement of the gingival mucosa, but the molecul...

Objective: Epidemiologic studies provide strong evidence that chronic psychosocial stress and depression increase the risk of several systemic diseases disorders. The current research aimed to investigate association between stress, with Periodontal Disease indices. Material Methods: study counted 280 individuals, males females, 40–65 years age, were collected through a clinical examination mod...

Periodontal disease is a pathological inflammatory condition of the periodontal tissues surrounding teeth, including Human Gingival Fibroblasts (HGF) which one major components tissue formation in periodonsium. HGF regeneration with accelerating proliferation engineering therapy needs. Generally, using regenerative materials from cow or pig as therapies, but these have some flaws so this resear...

We have previously reported that salivary glycine and proline levels are increased to nearly butanoate level in elderly people. In order to identify the source of glycine and proline, we performed high-performance liquid chromatography analysis of amino acid production to a total of seven oral cells before and after stimulation with inflammation inducers. We found that production of amino acids...

Human beta-defensin-1 (hBD-1) is a member of the family of small cationic antimicrobial peptides that have been identified in several mucosal epithelia. Because human gingival epithelium is a site that is constantly challenged by oral microorganisms, we examined the expression of hBD-1 in human gingival epithelial and fibroblast cell cultures and tissue samples. Cell cultures were challenged wi...

N-acetylcysteine (NAC) is an anti-oxidant drug that has been used as a mucolytic agent and a paracetamol antidote for many years. This study was designed to determine the efficacy of the adjunctive use of NAC for periodontal treatment. Thirty subjects with moderate-to-severe chronic periodontitis were randomized to surgery with NAC (600 mg; S-NAC), surgery only (S-nonNAC), and healthy control g...

background and aim . gingival recession as the apical migration of the gingival margin that results in exposure of the cementoenamel junction (cej) and the root surface. in this case series we aimed to demonstrate a combination technique using semilunar coronally positioned flap with free gingival graft for root coverage. materials and methods . a total of 12 healthy subjects, 25-45 years of ag...

BACKGROUND The evidence for the efficacy of periodontal plastic surgery (PPS) in the treatment of recession defects has not yet been systematically evaluated. The objective of this review was to systematically review the efficacy of PPS in achieving root coverage in the treatment of localized gingival recession. The following surgical procedures have been considered in this review: guided tissu...

The 2 major forms of periodontitis, chronic (CP) and aggressive (AgP), do not display sufficiently distinct histopathological characteristics or microbiological/immunological features. We used molecular profiling to explore biological differences between CP and AgP and subsequently carried out supervised classification using machine-learning algorithms including an internal validation. We used ...