PURPOSE Low-grade inflammation, a common feature in type 2 diabetes (DM2), causes some chronic complications in these patients. The present study was aimed to evaluate the effects of ginger (Zingiber officinale) on pro-inflammatory cytokines (IL-6 and TNF-α) and the acute phase protein hs-CRP in DM2 patients as a randomized double-blind placebo controlled trial. METHODS A total of 64 DM2 pati...

PURPOSE The present randomized, double-blind, placebo-controlled study aimed to evaluate the effect of Zingiber officinale (ginger) consumption on some metabolic and clinical features of obesity. METHODS Eighty eligible obese women (aged 18-45 years) were randomly assigned to either ginger or placebo groups (receiving 2 g/day of ginger powder or corn starch as two 1 g tablets) for 12 weeks. B...

Ginger has known hypoalgesic and anti-inflammatory properties. The effects of an oral dose of ginger on quadriceps muscle pain, rating of perceived exertion (RPE), and recovery of oxygen consumption were examined during and after moderate-intensity cycling exercise. Twenty-five college-age participants ingested a 2-g dose of ginger or placebo in a double-blind, crossover design and 30 min later...

BACKGROUND Ginger is a natural dietary component with antioxidant and anti-carcinogenic properties. This study was conducted to evaluate the prophylactic effect of ginger extract on ethanol-induced reproductive toxicity in male rats by measuring the total homocysteine (tHcy), trace elements, antioxidant enzymes activity including glutathione peroxidase, superoxide dismutase (SOD) and catalase, ...

OBJECTIVE To investigate the effect of a ginger extract (EV.EXT35) on the symptoms of morning sickness. DESIGN Double-blind randomised placebo-controlled trial. SETTING A tertiary metropolitan teaching hospital, March 1999-November 1999. PARTICIPANTS The participants included 120 women less than 20 weeks pregnant, who had experienced morning sickness daily for at least a week and had had ...

The use of botanical medicine is ancient, and plant chemicals are still the backbone of our pharmacopoeia because more than 50 % of drugs used in Western pharmacopoeia are isolated from herbs or derived from modification of chemicals first found in plants. Zingiber officinale Roscoe. (Ginger) is a spice that has been used from two thousand years ago as a medicine in several Asian countries. Rec...

BACKGROUND Ginger is one of the most important spice crops and traditionally has been used as medicinal plant in Bangladesh. The present work is aimed to find out antioxidant and anticancer activities of two Bangladeshi ginger varieties (Fulbaria and Syedpuri) at young age grown under ambient (400 μmol/mol) and elevated (800 μmol/mol) CO2 concentrations against two human breast cancer cell line...

The present study aimed to examine the antiproliferative potentiality of an extract derived from the medicinal plant ginger (Zingiber officinale) on growth of breast cancer cells. Ginger treatment suppressed the proliferation and colony formation in breast cancer cell lines, MCF-7 and MDA-MB-231. Meanwhile, it did not significantly affect viability of nontumorigenic normal mammary epithelial ce...

OBJECTIVE To study the effect of fine powder of ginger on lipid level in volunteer patients. METHODS This is a double blind controlled clinical trial study in 2 cardiac clinics Cardiac Disease Clinic, Babol, north of Iran, between April to May 2004. We randomly divided the patients with hyperlipidemia into 2 groups, treatment group (receiving ginger capsules 3 g/day in 3 divided doses) and pl...

Effects of different freezing rates and four different thawing methods on chemical composition, microstructure, and color of ginger were investigated. Computer simulation for predicting the freezing time of cylindrical ginger for two different freezing methods (slow and fast) was done using ANSYS (®) Multiphysics. Different freezing rates (slow and fast) and thawing methods significantly (P < 0...