The demand for accurate and reproducible phenotyping of a disease trait increases with the rising number of biobanks and genome wide association studies. Detailed analysis of histology is a powerful way of phenotyping human tissues. Nonetheless, purely visual assessment of histological slides is time-consuming and liable to sampling variation and optical illusions and thereby observer variation...

Davidsons Hygiene and Diseases of Warm Climates, states that, " although when seen alive m the blood, the embryo, diurna resembles so closely F. nocturna as to be practically indistinguishable therefrom; a singular difference is observable between the species when seen post mortem on dried and stained slides of thickest blood films." This is that the F. nocturna is arranged in graceful curves, ...

statement of problem: odontogenic keratocysts (okc) make up 10-12% of all developmental cysts with dental origin. okcs are classified into parakeratotic and orthokeratotic types, with completely different clinical features. in order to investigate biological behavior of okcs, an immunohistochemical study was designed, using ki-67 antigen as proliferation marker and p53 protein as tumor suppress...

BACKGROUND It is extensively supposed that vegetarian diet could affect cancer progress and increase the influence of formal chemotherapy. OBJECTIVES The present study was designed to determine the effect of the ethanol Bane skin extract against chemo resistant prostate cancer PC3 cells. MATERIALS AND METHODS PC3 and L929 cells were cultivated and then incubated in the ethanol Bane skin ext...

BACKGROUND "TBDx" is an innovative smear microscopy system that automatically loads slides onto a microscope, focuses and digitally captures images and then classifies smears as positive or negative using computerised algorithms. OBJECTIVES To determine the diagnostic accuracy of TBDx, using culture as the gold standard, and compare this to a microscopist's diagnostic performance. METHODS T...

Objective: The virtual slides are high-magnification whole digital images of histopathological tissue sections. The existing virtual slide system, which is optimized for scanning flat and smooth plane slides such as histopathological paraffin-embedded tissue sections, but is unsuitable for scanning irregular plane slides such as cytological smear slides. This study aims to develop a virtual sli...

This research was conducted on ten glass slides selected from the histopathology evaluation chickens. Five slides of control's chickens healthy and five slides of chickens infected experimentally with chicken anemia virus (CAV slide) between one and twenty-one days post infection (PI), they were analyzed in magnifications of 200x and 400x. Histopathology showed severe bone marrow hypoplasia to ...

In diagnostic histopathology, hematoxylin and eosin (H&E) staining is a critical process that highlights salient histological features. Staining results vary between laboratories regardless of the histopathological task, although method does not change. This variance can impair accuracy algorithms histopathologists’ time-to-insight. Investigating this help calibrate stain normalization task...