Aneurysmal bone cyst, first described by Jaffe and Lichtenstein I in 1942 as a rare, localized tumor of the long bones and spinal vertebrae, characterized by the "blowout distention" of the skeletal contour on a radiograph.2 This neoplasm, usually found in children and young adults, constitutes 1.4 percent of all primary bone tumors.3 The cyst is occasionally associated with other tumors of the...

BACKGROUND/AIMS To report a case of subretinal bone formation after the treatment with denosumab for a giant cell tumor of the sphenoid, which had recurred after surgical resection. METHODS The clinical history and fundus findings including imaging, histologic and immunohistochemical features of the primary tumor and subretinal lesion were reviewed. RESULTS A 14-year-old boy was evaluated f...

INTRODUCTION Giant cell tumor (GCT) of bone is a borderline lesion of bones, meaning that in certain conditions it could be transforming in malignant tumor. This article describes the clinical outcome of patients with giant cell tumor of bone and discusses the surgical options for this lesion corelating with histopathological grade. MATERIAL AND METHODS From 2007 to 2015, 15 patients who met ...

Giant cell tumor of the small bones, particularly the carpal bones of the hand, is exceedingly rare. We present a case report of giant cell tumor of the capitate in a 24 year-old female with 10 years postoperative follow-up. Although carpal bones are extremely unusual location, orthopedic surgeons should always keep in mind that differential diagnosis must include giant cell tumor of bone whene...

Giant cell tumor of bone rarely occurs in the skull, particularly in the temporal bone, it is rarest one. They are very aggressive and have tendency to local recurrence and late malignant change with metastases. Multiple bits of grey-brown tissue were received in 10% formalin fixative. These were processed in histokinette, embedded in paraffin and blocks were made with the help of microtome, th...

The management of giant cell tumor of the proximal humerus that extends to the joint is challenging. Here, we report a case of proximal humerus giant cell tumor with cortical bone destruction extending to the shoulder joint. Pre-operative selective arterial embolization induced peripheral tumor ossification. Subsequently, the lesion was removed by intralesional curettage, and the cavity was fil...

We report a case of giant cell tumor occurring in a 12-year-old girl. Radiographs revealed a radiolucent lesion in the proximal epi-metaphysis of the right fibula, which was initially diagnosed as an aneurysmal bone cyst. Magnetic resonance imaging showed an expansile intramedullary lesion with focal multiloculated fluid-fluid levels and also solid mass in the proximal metaphysis. The latter so...

  Background: Tumors involving the hand skeleton are rare. However, a basic knowledge of hand tumors is necessary for every clinician. This is due to the importance of distinguishing typical benign tumors from life or limb threatening malignant ones. Methods: This study is a review of 99 cases of osseous hand tumors presented to the department of orthopedic surgery, Imam Khomeini Hospital in Te...