anti-adhesion therapy represents a potentially promising avenue for the treatment and prevention of tuberculosis in a post-antibiotic era. adhesins are surface-exposed microbial structures or molecules that enable pathogenic organisms to adhere to host surfaces, a fundamental step towards host infection. although several mycobacterium tuberculosis adhesins have been identified, it is predicted ...

background: tuberculosis continues to be a serious public health problem causing nearly three million deaths per year all over the world. despite major improvement in diagnosis, it is not possible to control the disease in the absence of surveillance treatment, and follow-up programs. objectives: this research was designed to study the frequency of mycobacterium tuberculosis among specimens ref...

In contrast to the high incidence of pulmonary tuberculosis in underdeveloped or developing countries, genital tuberculosis is rarely observed. Genital tuberculosis (GT) is a major pelvic factor causing infertility. The role of GT in female infertility should not be forgotten, especially in women under 40 years of age. GT should be treated before treating infertility. Nevertheless, in spite of ...

a 25-year-old female presented to the infertility opd with complaints of secondary infertility and pain lower abdomen with watery discharge for the past five days. she had history of undergoing hysterosalpingography in a private hospital ten days back. the interventions included drainage of pyometra, endometrial biopsy for routine and afb smear/ culture,  confirmation of diagnosis by m rna-base...

BACKGROUND Genital tuberculosis is a chorionic disease and mostly occurs by haematogenous spread from extra genital source like lungs, peritoneum, lymph nodes and bones. Transmission through a sexual intercourse is also possible. Since the majority of patients are in reproductive ages, involvement of fallopian tubes and endometrium cause infertility in patients. CASES Reviewing 4 cases of fem...

Background: Diabetes is an important metabolic disease with myriad manifestations and complications, affecting many people. Cutaneous infections impact numerous diabetic patients. Among different bacterial infections in diabetic patients, the infections caused by mycobacteria other than Mycobacterium tuberculosis (MOTT) eventuate in complications owing to the paucity of accurate detection...

Female genital tuberculosis is an uncommon cause of infertility in our environment and is hardly looked for as part of routine assessment of infertility. With a resurging incidence of Tuberculosis in the face of the HIV pandemic, it is important to always have genital tuberculosis in mind especially when no other cause is found for the infertility. We report a case of a patient with 15 years in...

Identification of Mycobacterium tuberculosis and Rifampin Resistance in Pulmonary Extra-pulmonary Clinical Specimens Using the Gene Xpert MTB/RIF Assay

Tuberculosis is a vagarious infectious disease that generally affects the lungs. Accordingly, in some cases, it can also affect the liver and kidney. Host genetic may affect tuberculosis caused by bacillus Mycobacterium tuberculosis. The main risk factors for the disease are a weakened immune system because of diabetes, some cancers, HIV/AIDS, severe kidney disease, cancer treatment, a...

background: beijing family of mycobacterium tuberculosis (m. tuberculosis) is widespread in asia and has been involved in outbreaks of multidrug-resistant tuberculosis in various parts of the world.  the aim of the current study was to evaluate the frequency of beijing family of m. tuberculosis in patients with tuberculosis in mashhad, iran. materials and methods: totally, 72 specimens of m. tu...