The conversion of Earth's land surface to urban uses is one of the most irreversible human impacts on the global biosphere. It drives the loss of farmland, affects local climate, fragments habitats, and threatens biodiversity. Here we present a meta-analysis of 326 studies that have used remotely sensed images to map urban land conversion. We report a worldwide observed increase in urban land a...

The two dominant schemes for rule learning C and RIPPER both operate in two stages First they induce an initial rule set and then they re ne it using a rather com plex optimization stage that discards C or adjusts RIPPER individual rules to make them work better together In con trast this paper shows how good rule sets can be learned one rule at a time with out any need for global optimization ...

BACKGROUND In 2014, almost half of the global tuberculosis deaths occurred in the World Health Organization (WHO) African Region. Approximately 21.5 % of the 6 060 742 TB cases (new and relapse) reported to the WHO in 2014 were in the African Region. The specific objective of this study was to estimate future gross domestic product (GDP) losses associated with TB deaths in the African Region fo...

The global digital divide as a concept is intuitively understood by most academicians, politicians and public policy makers. However, to date little empirical work exists to explain differences in per country access to Information and Communication Technologies (ICTs). The research that does exists places heavy influence on the impact of country wealth, as measured by Gross Domestic Product (GD...

In the last decade, a few papers have analysed the consequences of achieving the greenhouse gas concentration levels necessary to maintain global temperature increases below 2 degrees Celsius above preindustrial levels. Most models and scenarios assume that future trends in global GDP will be similar to the growth experienced in the past century, which would imply multiplying current output nin...

Global biodiversity conservation is seriously challenged by gaps and heterogeneity in the geographical coverage of existing information. Nevertheless, the key barriers to the collection and compilation of biodiversity information at a global scale have yet to be identified. We show that wealth, language, geographical location and security each play an important role in explaining spatial variat...

We use the ratio of growth in global military expenditures to gross domestic product (GDP) to capture ex ante expectations of political instability and explore the relation between this measure and returns. In a standard global asset pricing framework with 44 countries, this measure helps to explain cross-country return differences. Furthermore, emerging countries have greater exposure to inter...

INTRODUCTION Ischemic heart diseases (IHDs) are the leading cause of mortality worldwide. However the global burden of IHD has been concentrated on developing countries, where limited research efforts have been made to address these needs. This study aimed to understand the global distribution of IHD research activities by looking at the countries' burden of disease, income and development data...

As a means of generating homogeneous populations of elongation complexes with the RNA polymerases encoded by phages T7 and SP6, transcription has been carried out in vitro on templates associated with the Gln-111 mutant of EcoRI endonuclease. The Gln-111 protein, as a result of a single amino acid substitution at position 111, lacks cleavage function yet shows higher than wild-type affinity for...