Background: Control of fungi is problematic, since effective methods for intervening fungal infection or contamination, especially for those resistant to drugs/fungicides, are often very limited. Generally regarded as safe (GRAS) agents, such as natural compounds or their structural analogs could be potential sources of sustainable antifungal agents. As a proof of concept, antifungal efficacy o...

Zinc oxide (ZnO) has been used for many years in the pharmaceutical, cosmetic, paint, textile, and food industries coating surfaces, absorbing UV rays due to its antimicrobial properties nanoscale it identified as important chemical decontamination. can be found foods well allowed daily intake adults reported 8-11 mg. Oxide Nanoparticles (ZnO-NPs) are generally regarded safe (GRAS) being stable...

In past few years, global neutraceutical market has witnessed an increased recognition to the probiotic supplements. Consumers are becoming more aware about food supplements which could enhance the immunity and reduce the medical incidences in their life. The probiotic approach of modulating the gut flora to re-establish the normal health has gained much creditability among modern therapeutic s...

UNLABELLED 5-Aminolevulinic acid (ALA), a nonprotein amino acid involved in tetrapyrrole synthesis, has been widely applied in agriculture, medicine, and food production. Many engineered metabolic pathways have been constructed; however, the production yields are still low. In this study, several 5-aminolevulinic acid synthases (ALASs) from different sources were evaluated and compared with res...

The Gram-positive bacterium, Bacillus subtilis and related species are widely used as hosts for the extracellular production of industrially worthy enzymes, such as amylases, proteases, xylanase, and lipases (Braun et al., 1999; Tjalsma et al., 2000; Westers et al., 2004). These species possess a very high capacity for secreting a variety of exoenzymes into the growth medium, thereby reducing d...

Lactic acid bacteria (LAB) are a group of Gram-positive, non-sporulating, low-GC-content bacteria that comprise 11 bacterial genera, such as Lactococcus, Lactobacillus, Leuconostoc, Streptococcus and others (Stiles & Holzapfel, 1997). LAB have a generally regarded as safe (GRAS) Food and Drug Administration (FDA) status, and some strains of different LAB species exhibit also probiotic propertie...

Conflicts of interest inmedical research, education, andpractice arewell known to increase the risk of undue influence by corporate sponsors. Because conflicts of interest are soprevalent and troublesome, the Institute of Medicine (IOM) was asked to develop guidelines for dealing with them. An IOM committee reviewed the substantial body of evidence demonstrating that financial ties with pharmac...

Among other fermentation processes, lactic acid fermentation is a valuable process which enhances the safety, nutritional and sensory properties of food. The use of starters is recommended compared to spontaneous fermentation, from a safety point of view but also to ensure a better control of product functional and sensory properties. Starters are used for dairy products, sourdough, wine, meat,...

The object of this paper is to call attention to a group of tumors, the nature of which has hitherto escaped general recognition, and to point out their distinguishing characteristics. These tumors are rich in cells which may vary nmch in size and shape. They may be pervaded by connective tissue by which the cells are arranged in more or less definite alveoli. Blood vessels accompanied by conne...

Laktik asit bakterileri pek çok fermente ve probiyotik gıdanın bünyesinde yer alan faydalı bakterilerdir. Bu önemli kılan özellikleri arasında GRAS (Generally Recognized As Safe) statüde olmaları ürettikleri antimikrobiyal metabolitler bulunmaktadır. bakterilerinin ürettiği antagonistik etkiye sahip en metabolit bu gruba adını veren laktik olup; bunun yanısıra hidrojen peroksit, asetik asit, di...