Astrocytes express the sodium-dependent glutamate transporters GLAST and GLT-1, which are critical to maintain low extracellular glutamate concentrations. Here, we analyzed changes in their expression and function following a mechanical lesion in the CA1 area of organotypic hippocampal slices. 6-7 days after lesion, a glial scar had formed along the injury site, containing strongly activated as...

OBJECTIVES The nuclear protein high mobility group protein box 1 (HMGB1) is a proinflammatory mediator that belongs to the alarmin family of proinflammatory mediators, and it has recently emerged as a key player in different acute and chronic immune disorders. Several lines of evidence demonstrate that HMGB1 is actively released extracellularly from immune cells or passively released from necro...

let $g$ be a finite group and $pi_{e}(g)$ be the set of element orders of $g $. let $k in pi_{e}(g)$ and $s_{k}$ be the number of elements of order $k $ in $g$. set nse($g$):=${ s_{k} | k in pi_{e}(g)}$. in this paper, it is proved if $|g|=|$ pgl$_{2}(q)|$, where $q$ is odd prime power and nse$(g)= $nse$($pgl$_{2}(q))$, then $g cong $pgl$_

Abstract When a glued laminated timber (GLT) beam with round hole is subjected to shear force and bending moment, the will crack fail due large tensile stress perpendicular grain stresses. If stresses acting on are known, it possible estimate fracture load. However, necessary obtain by finite element analysis, which very time consuming. In this study, easily load, we proposed formula bearing ca...

An approach to estimate the tire{road friction during normal drive using only the wheel slip, that is, the relative diierence in wheel velocities, is presented. The driver can be informed about the maximal friction force and be alarmed for sudden changes. Friction related parameters are estimated using only signals from standard sensors in a modern car, and the physical relation between these p...

OBJECTIVE Glutamate transporter-1 (GLT-1) maintains low concentrations of extracellular glutamate by removing glutamate from the extracellular space. It is controversial, however, whether upregulation of GLT-1 is neuroprotective under all ischemic/hypoxic conditions. Recently, a neuroprotective effect of preconditioning with a β-lactam antibiotic ceftriaxone (CTX) that increases expression of G...