Drought stress is one of the most determinative factors of agriculture and plays a major role in limiting crop productivity. This limitation is going to rising through climate changes. However, plants have their own defense systems to moderate the adverse effects of climatic conditions. MicroRNA-mediated post-transcriptional gene regulation is one of these defense mechanisms. The root endophyti...

ABSTRACT Gene-editing technologies, ie those able to make changes in the DNA of an organism, are object global competition and a regulatory race between countries regions. There is attempt craft legal frameworks protective enough for users, but flexible developers gene-editing technologies. This article examines imaginary built into framing EU-level regulation human technologies identifies its ...

Many complex human phenotypes exhibit sex-differentiated characteristics. However, the molecular mechanisms underlying these differences remain largely unknown. We generated a catalog of sex in gene expression and genetic regulation across 44 tissue sources surveyed by Genotype-Tissue Expression project (GTEx, v8 release). demonstrate that influences levels cellular composition samples body. A ...

Background: Transforming growth factor (TGF)-β is over-expressed in a wide variety of cancers such as lung adenocarcinoma. TGF-β plays a major role in cancer progression through regulating cancer cell proliferation and remodeling of the tumor micro-environment. However, it is still a great challenge to explain the phenotypic effects caused by TGF-β stimulation and the effect of TGF-β stimulatio...

Ubiquitin - proteasome system (UPS), the major protein degradation pathway in the cells, typically degrades short - lived and damaged proteins and regulates growth and stress responses. This pathway is altered in various cancers, including Acute Lymphoblastic Leukemia (ALL). ALL begins with a change in bone marrow cells and is the most common type of leukemia in children under 15 years. UBE2Q1...

the aim of the present study was to investigate the effect of endurance training on syd gene expression in motor neurons of rats with diabetic neuropathy. 12 wistar male rats were randomly assigned to 3 groups (each group 4 subjects): diabetic trained (dt), diabetic untrained (dc) and healthy control (hc). two weeks after stz injection to induce diabetes, diabetic neuropathy was demonstrated by...