The scientific review presents the biogenesis of miRNAs. To write article, information was searched using databases Scopus, Web Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, Cochrane Library, CyberLeninka. article shows stages formation mature It is noted that duplex RNAs resulting from DICER-mediated cleavage interact with Argonaute (AGO) proteins to form an effector RNA-ind...

spinal cord injury (sci) in humans remains a devastating and incurable disorder. a very important obstacle in axonal regeneration after spinal cord injury is astroglial scaring. the use of self-assembling peptide nanofiber, a hydrogel mimicking extracellular matrix, has been suggested as a scaffold for spinal cord regeneration and inhibition of astrogliosis. however, neurogenesis potential of l...

Software development by assembling components represents a very promising way for the design of high quality software at lower costs. The assembly is specified by the Architecture Description Languages (ADL). ArchJava is an ADL that is characterized by its independence from the application domain and its close position to the implementation level, thus making it very attractive for practitioner...

Invertebrates' immune defense mechanisms play a critical role in pathogen recognition and elimination. De novo assembly annotation of the Argopecten ventricosus transcriptome were performed for immune-related gene identification. Scallops (height: 4.4 cm) challenged with inactivated Vibrio parahaemolyticus IPNGS16. The RNA from different tissues was pooled single cDNA library construction seque...

KnowSeq R/Bioc package is designed as a powerful, scalable and modular software focused on automatizing assembling renowned bioinformatic tools with new features functionalities. It comprises unified environment to perform complex gene expression analyses, covering all the needed processing steps identify signature for specific disease gather understandable knowledge. This process may be initia...

Self-assembling tile systems are a model for assembling DNAbased nano artefacts. In the currently known constructions, most of the effort is put on garanteeing the size of the output object, whereas the geometrical efficiency of the assembling of the shape itself is left aside. We propose in this paper a framework to obtain provably time efficient selfassembling tile systems. Our approach consi...

Different polysaccharide-based supramolecular polycations were readily synthesized by assembling multiple β-cyclodextrin-cored star polycations with an adamantane-functionalized dextran via host-guest interaction in the absence or presence of bioreducible linkages. Compared with nanoplexes of the starting star polycation and pDNA, the supramolecular polycation/pDNA nanoplexes exhibited similarl...

We present a probabilistic logic program to generate an educational puzzle that introduces the basic principles of next generation sequencing, gene finding and the translation of genes to proteins following the central dogma in biology. In the puzzle, a secret ”protein word” must be found by assembling DNA from fragments (reads), locating a gene in this sequence and translating the gene to a pr...