The building block of the surface detector of the Pierre Auger Observatory is a water Cherenkov tank. The response to shower particles is simulated using a dedicated program based on GEANT4. To check the simulation chain, we compare the simulated signals produced by cosmic muons at various zenith angles with experimental data from a special Cherenkov detector equipped with a muon hodoscope. The...

The TIRAMISU collaboration gathers expertise from biologists, physicists, radiochemists and geologists within the Zone-Atelier Territoires Uranifères (ZATU) in France to study response of microorganisms living naturally radioactive mineral springs. Mineral springs are isolated ecosystems, extremely stable over geological time scales, which display different physicochemical radiological paramete...

Introduction: We describe a nephron-based dosimetry model for renal toxicity for radiopharmaceutical therapy suited to the nonuniform activity distribution of radiopharmaceutical. In radiopharmaceutical therapy, renal toxicity is observed while whole-kidney and renal cortex absorbed dose values are below toxicity thresholds established by external beam and targeted radiope ptid...

The employment of Monte Carlo simulations in the applied nuclear physics techniques has increased with the data processing capabilities of the commercial personal computers. Since the inclusion of the low-energy electromagnetic interactions in GEANT4, this Monte Carlo simulation toolkit has produced results which reveal its promising utilization in radiation dosimetry, radiation protection and ...

Proton beams in medical applications deal with relatively thick targets like the human head or trunk. Thus, the fidelity of proton computed tomography (pCT) simulations as a tool for proton therapy planning depends in the general case on the accuracy of results obtained for the proton interaction with thick absorbers. GEANT4 simulations of proton energy spectra after passing thick absorbers do ...

The determination of the microscopic dose-damage relationship for DNA in an aqueous environment is of a fundamental interest for dosimetry and applications in radiation therapy and protection. We combine geant4 particle-scattering simulations in water with calculations concerning the movement of biomolecules to obtain the energy deposit in the biologically relevant nanoscopic volume. We juxtapo...