objective: iqspect is an advanced high-speed spect modality for performing myocardial perfusion imaging (mpi), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. the aim of this study was to compare iqspect compared with conventional spect interms of performance based on standard clinical protocols. in addition, we examined the concordance between conventional...

UNLABELLED We investigated the reproducibility of an automatic quantitative algorithm for measuring regional myocardial wall motion and systolic thickening. METHODS 99mTc-sestamibi gated myocardial SPECT with dipyridamole stress was performed twice consecutively on 31 patients with known or suspected coronary artery disease, with the patients in the same position for each scan. With AutoQUANT...

A 67 years old woman was referred to nuclear medicine center for myocardial perfusion imaging (MPI) for assessment of ischemic heart dieses (IHD).She had a history of atypical chest pain and dyspnea since about 10 days before admission. The MPI SPECT/CT was performed by stress/redistribution Tl-201 protocol. MPI was interpreted as relatively good coronary flow with no appreciable stress induced...

Citation for published version (APA): Fransson, H., Hedeer, F., Arévalo, C., Carlsson, M., Engblom, H., Ubachs, J., ... Heiberg, E. (2011). Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard. Journal of Nuclear Cardiology, 18(5), 874-885. DO...

UNLABELLED Electrocardiographically (ECG) gated myocardial SPECT with (99m)Tc-tetrofosmin has been used widely to assess left ventricular (LV) function. However, the accuracy of variables using ECG gated myocardial SPECT with beta-methyl-p-(123)I-iodophenylpentadecanoic acid (BMIPP) has not been well defined. METHODS Thirty-six patients (29 men, 7 women; mean age, 61.6 +/- 15.6 y) with ischem...

OBJECTIVE To compare exercise tolerance testing (ETT) with gated single photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) risk stratification in women with an intermediate to high CAD pretest risk and known estrogen status (ES). BACKGROUND SPECT-MPI is an effective test for risk stratifying patients with stable angina. However in women, the current guidelines recomm...

UNLABELLED Gated myocardial perfusion SPECT has been used to calculate ejection fraction (EF) and end-diastolic volume (EDV) and has correlated well with conventional methods. However, the comparative accuracy of and correlations across various types of gated SPECT software are not well understood. METHODS Mathematic phantoms of cylindric-hemispheric hybrid models, ranging in volume from 34 t...

We prospectively investigated whether 20'TI single-photon emission computed tomography (SPECT) could accurately diagnose the presence and quantify the extent of acute myocardial infarction when compared with infarct size assessed by plasma MB-creatine kinase activity. Thirty patients with enzymatic evidence of infarction were imaged within 12-36 hours of chest pain (mean, 23.4 hours). No patien...

UNLABELLED SPECT and PET myocardial perfusion images show greater myocardial intensity and homogeneity in systole than diastole because of greater systolic myocardial thickness, less partial volume loss, and enhanced activity recovery. Consequently, conventional myocardial perfusion images obtained from whole cardiac cycles have lower myocardial intensity and greater heterogeneity than systolic...

atients with type 2 diabetes mellitus (DM) have a higher risk of cardiovascular events and death than those without the disease.1–6 Coronary artery disease (CAD) in diabetic patients is frequently silent.7–9 To maximize the effective treatment of cardiovascular disease in patients with DM, it is important to objectively identify CAD in asymptomatic subjects in a noninvasive way as early as poss...