Detailed information about the relationships between structures and properties/activities of peptides as drugs and nutrients is useful in the development of drugs and functional foods containing peptides as active compounds. The bitterness of the peptides is an undesirable property which should be reduced during drug/nutrient production, and quantitative structure bitter taste relationship (QSB...

Normal human T cells proliferate vigorously when stimulated with autologous non-T cells. This autologous mixed lymphocyte reaction (MLR) between T and non-T cells was defective in patients with active systemic lupus erythematosus (SLE). In contrast, T cells and non-T cells from active SLE patients behaved normally as responding and stimulating cells, respectively, in the allogeneic MLR. The eti...

This article provides an overview of the current issues and challenges facing the nascent paradigm of minority language rights (MLR). It focuses on the theoretical points of dispute and tension with respect to MLR, as well as the challenges attendant upon their implementation in complex, multiethnic and multilingual contexts. The article acknowledges, but also responds to, key critiques of MLR ...

Multiple linear regression (MLR), adaptive network-based fuzzy inference system–ant colony optimization algorithm hybrid (ANFIS-ACOR) and artificial neural network–multilayer perceptron (ANN-MLP) were tested to model the bending strength of Glulam (glue-laminated timber) manufactured with a plane tree (Platanus orientalis L.) wood layer adhered different weight ratios (WR) modified starch/urea ...

The present study provides comparative evaluation of the ABR and MLR to 1 kHz brief tones in two groups of hearing-impaired subjects (noise-masked normally-hearing; and sensorineurally hearing-impaired adults), as well as a normally-hearing control group. Tones were presented at intensities from threshold to 80 /90 dB nHL. The results of this study show that: (1) the ABR and MLR to these low-fr...

Although immunoregulation of alloreactive human CTLs has been described, the direct influence of CD4(+) Tregs on CD8(+) cytotoxicity and the interactive mechanisms have not been well clarified. Therefore, human CD4(+)CD127(-)CD25(+)FOXP3(+) Tregs were generated in MLR, immunoselected and their allospecific regulatory functions and associated mechanisms were then tested using modified (51)Chromi...

In the present study, there was a complete lack of autologous MLR between responding T cells or T subsets and unirradiated or irradiated leukemic B cells or monocytes in all 20 patients with CLL, regardless of disease status, stage, phenotype, or karyotype of the disease. The stimulating capacity of unirradiated CLL B cells and CLL monocytes or irradiated CLL B cells was significantly depressed...

The purpose of this study was to implement a diffusion-weighted sequence for visualisation of mobile lipid resonances (MLR) using high resolution magic angle spinning (HR-MAS) (1)H MRS and to evaluate its use in establishing differences between tissues from patients with cervical carcinoma that contain cancer from those that do not. A stimulated echo sequence with bipolar gradients was modified...

Context: A Multivocal Literature Review (MLR) is a form of a Systematic Literature Review (SLR) which includes the grey literature (e.g., blog posts and white papers) in addition to the published (formal) literature (e.g., journal and conference papers). MLRs are useful for both researchers and practitioners since they provide summaries both the state-of-the art and –practice in a given area. M...

In the search for an accurate yet inexpensive method to predict thermodynamic properties of large hydrocarbon molecules, we have developed an automatic and adaptive distance-based group contribution (DBGC) method. The method characterizes the group interaction within a molecule with an exponential decay function of the group-to-group distance, defined as the number of bonds between the groups. ...