Choroideremia is a complex and rare disease that is frequently misdiagnosed due to its similar appearance to classic retinitis pigmentosa. Recent advances in genetic testing have identified specific genetic mutations in many retinal dystrophies, and the identification of the mutation of the CHM gene on the X chromosome 25 years ago has paved the way for gene replacement therapy with the first h...

Applications of vehicular networking are set to explode much in the way that Internet technology emerged in the early 1990s. The convergence of in-car navigation systems, highbandwidth wireless communications, protocols for highly-mobile ad hoc networks, and the inherent ability to instrument vehicles with sensing and control devices leads to many potential personal and community-based services...

BACKGROUND Mammary ductoscopy (MD) allows direct visualisation of the mammary ducts using sub-millimetre fiberoptic microendoscopes inserted through the ductal opening onto the nipple surface. The sharp clear magnified images are viewed on a video monitor. Such scopes have working channels that allow irrigation and ductal lavage for cytological analysis. MD can be performed under local anaesthe...

Globular clusters are stellar dynamical systems which evolve on stellar evolutionary and both internal and external dynamical timescales. Quantitative comparison of cluster properties with realistic evolutionary dynamical models is becoming feasible, and will underpin the subject in the next few years. A few examples of the types of analysis becoming possible are presented.

Autoimmune hepatitis (AIH) is a chronic progressive liver disease characterized by high levels of aminotransferases and autoantibodies, hypergammaglobulinemia, and interface hepatitis. AIH affects all races and all ages worldwide, regardless of sex, although a preponderance of females is a constant finding. The etiology of AIH has not been completely elucidated, but immunogenetic background and...

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The situation in particle physics today is highly analogous to that which existed in chemistry towards the end pf the 19th century. During the preceding two centuries, remarkable progress has been achieved in that discipline, progress that culminated in the periodic table of Mendeleyev. This table summarieed not only the realieation that our everyday matter is composed of basic building blocks,...

this paper seeks to examine the current situation of development in the middle east and particularly the challenges ahead of the region in attaining sustainable development and human development in the near future. the elitist theory is adopted as the conceptual framework for the research, since in the absence of institutionalization, the attitudes and behavior of power-holders serve as valid g...

Throughout the poorer countries of the world, millions of children live out their young lives in substandard institutions or in the streets. In times of war or political and economic upheaval, added numbers of children become homeless. At the same time, thousands of couples in the more advantaged countries of the West have demonstrated their eagerness to offer permanent homes to many of these c...