We here report on the furan oxidation methodology for interstrand cross-linking of RNA duplexes, which have a different structure and are more stiff, reactive and labile than their DNA counterparts. Through this mildly inducible approach, natural unmodified RNA can be selectively cross-linked in high yield. The method therefore has direct applications in the increasing number of RNA based techn...

Carbon nanothreads, which are one-dimensional sp3-rich polymers, combine high tensile strength with flexibility owing to subnanometer widths and diamond-like cores. These extended carbon solids constructed through pressure-induced polymerization of sp2 molecules such as benzene. Whereas a few examples nanothreads have been reported, the need for onset pressures (?17 GPa) synthesize them preclud...

In the title compound, C(15)H(11)BrO(3), the dihedral angle between the naphtho-furan ring system (r.m.s. deviation = 0.022 Å) and the side chain is 4.50 (2)°. In the crystal, short Br⋯Br [3.4435 (7) Å] contacts propagating along [010] in a zigzag manner and weak π-π inter-actions [shortest centroid-centroid separation = 3.573 (2) Å] directedalong [100] are observed.

The furan ring in the title compound, C(27)H(20)N(2)O(2), adopts a twisted conformation about the sp(3)-sp(3) bond. The mol-ecular structure is stabilized by an intra-molecular C-H⋯O inter-action which generates an S(6) ring motif. The crystal packing is stabilized by N-H⋯O and C-H⋯O inter-actions generating centrosymmetric R(2) (2)(18) and C(6) chain motifs, respectively. A weak C-H⋯π inter-ac...

Hyperolactone C is prepared from furan 4. The key transformation is a tandem Claisen rearrangement/lactonization.

The title compound, C11H10BrNO3, is close to planar with the benzo-furan unit and the ester group subtending a dihedral angle of 5.25 (2)°. The mol-ecular structure features an intra-molecular N-H⋯O inter-action. In the crystal, N-H⋯O hydrogen bonds involving carboxyl O-atom acceptors generate a chain extending along [201].

The mol-ecule of the title compound, C(10)H(6)O(4)S(2), has crystallographically imposed twofold symmetry. The dihedral angle formed by the furan rings is 80.90 (8)°. In the crystal, mol-ecules are linked by weak C-H⋯O hydrogen bonds into chains running parallel to the a axis [C-S-S-C torsion angle = 82.04 (11)°].

The applications of lignocellulosic wastes to produce a wide variety products, including biochemicals, biomaterials, and biofuels, can be an effective solution for utilizing these valuable waste materials. In this study, the production furan building blocks from bagasse fibers was investigated by treating unbleached with NMMO, [Bmim]Cl, TMAH at different temperatures using AlCl3 CrCl2 as cataly...