Increasing evidence suggests that colistin monotherapy is suboptimal at currently recommended doses. We hypothesized that front-loading provides an improved dosing strategy for polymyxin antibiotics to maximize killing and minimize total exposure. Here, we utilized an in vitro pharmacodynamic model to examine the impact of front-loaded colistin regimens against a high bacterial density (10(8) C...

Vernonia galamensis Cass is a huge potential industrial crop with very high content of vernolic acid in the seed oil. The experiment was carried out to determine the effect of inter- and intra- row spacing on the yield and yield related traits of Vernonia galamensis Cas.The experiment was conducted for two years during 2014-2015 on experimental field of Wondo Genet Agricultural research center,...

So much attention is focused on the current HIV/AIDS epidemic in Africa that there is a tendency to overlook the grievous burden of disease from which the peoples of that Continent have suffered for centuries. This paper, based on letters sent in 1953/54 by a young doctor in Sierra Leone to his parents in Scotland, together with extracts from Makeni Hospital records of the same period, provides...

spreading faba bean (vicia faba) cultivation can enhance the sustainability of cropping systems and have other important benefits. however, there is little information on the various aspects of production management for this crop. then, this experiment was carried out to study the response of some agronomic characteristics of faba bean cv barakat to inter- (15, 30, 45 and 60 cm) and intra-row (...

A new species of Sphaerodoridium Lützen, 1961 (Polychaeta: Sphaerodoridae) collected off Iceland during the BIOICE programme is described. Sphaerodoridium guerritai sp. nov. is mostly present in waters around the northern half of Iceland, and seems to be common in soft bottoms at depths of 49-1253 m. It is mainly characterized by having macrotubercles which are provided with a long stalk which ...

Injury characteristics of child passengers in accidents are summarized in this paper. Based on the accident data about child passengers from 2011 to 2017 collected in the National Automobile Accident In-Depth Investigation System (NAIS), the analysis of the patterns of the traffic accident where child passengers are involved and injury characteristics of child passengers in the aspects of crash...

The front-illuminated (FI) CCDs in the Advanced CCD Imaging Spectrometer (ACIS) on the Chandra X-ray Observatory (Chandra) were damaged in the extreme environment of the Earth’s radiation belts, causing charge traps that result in enhanced charge transfer inefficiency (CTI) during parallel readout. This causes row-dependent gain, event grade ‘morphing’ (spatial redistribution of charge) and ene...

in order to study the effect of row spacing and plant density on quantity and quality yield of soybean in weed competitive condition, a field experiment was carried out at research farm of yasuj agricultural college in summer of 2011. experiment arrangement was split factorial base on randomized complete block design with three replication. the main factor included weed ( in two levels of contr...

Physical demands such as distance covered and speed of individual players during football, handball, rugby league (13 players), and rugby union (15 players, hereinafter “rugby”) games were analyzed to create training plans suitable for each sport (Tanisho et al., 2009; Tanaka et al., 2002; Gabbett et al., 2012). In the 1980s, Kawase et al. (1988) conducted research on total distances covered pe...

0039-6028/$ see front matter 2009 Elsevier B.V. A doi:10.1016/j.susc.2009.10.002 * Corresponding author. E-mail address: [email protected] (A.J.H. McGa Atomic oxygen embedment into a Cu(100) surface is studied by density functional theory calculation and the nudged elastic band method. As the oxygen coverage increases on the unreconstructed surface from 0.25 monolayer (ML) to 0.75 ML, the energ...