The adult kidney contains a population of low-cycling cells that resides in the papilla. These cells retain for long periods S-phase markers given as a short pulse early in life; i.e., they are label-retaining cells (LRC). In previous studies in adult rat and mice, we found that shortly after acute kidney injury many of the quiescent papillary LRC started proliferating (Oliver JA, Klinakis A, C...

BACKGROUND Derivatives of isoxazolopyridines exhibit diverse biological activity. One method of synthesizing isoxazolo[4,5-b]pyridines is Friedlander condensation. OBJECTIVES To establish the conditions necessary for conventional and microwave synthesis of new 3,5,6,7-tetrasubstituted isoxazolo[4,5-b]pyridines and their antiproliferative activity. MATERIAL AND METHODS The substrates in the ...

A simple and efficient method for the synthesis of quinolines and polycyclic quinolines using Li+ modified nanoporous Na+-montmorillonite is described. This new nanocatalyst proceeds via Friedlander annulation under solvent-free conditions. It describes our observations about a trend of catalytic activity of Lithium cation in nanoporous Na+-montmorillonite. In this study, several types of 1,3-d...

Abstract Let $\Sigma $ be a compact surface with boundary. For given conformal class c on the functional $\sigma _k^*(\Sigma ,c)$ is defined as supremum of k th normalized Steklov eigenvalue over all metrics in . We consider behavior this moduli space classes A precise formula for limit ,c_n)$ when sequence $\{c_n\}$ degenerates obtained. apply to study natural analogs Friedlander–Nadirashvili ...