temporomandibular disorders (tmd) are clinical conditions characterized by pain and sounds of the temporomandibular joint (tmj). this study was designed to assess the effect of low-level laser therapy (lllt) on healing of osteoarthritis in rats with tmd.thirty-two male wistar rats (250-200 g) were housed in standard plastic cages. after injection of complete freund's adjuvant into the tmj, rats...

echinococcosis is one of the world’s relevant zoonoses, affecting both humans and their domestic animals and caused by infection with the metacestode stage of the dog tapeworm, echinococcus granulosus. in the present study, twenty mice were randomly divided into 4 groups of 5. each mouse in groups 1, 2 and 3 was immunized with 100 μg of hydatid cyst fluid protein, protoscolex and adult worms of...

Arthritis-induced adjuvant (AIA) is an established animal model reflecting several clinical manifestations of human arthritis. It provides more understanding pathogenesis and pathways involved in arthritic development for testing various treatment modalities. Complete Freund’s (CFA) one the most known algogenic agents used to develop AIA rodent model. Its wide application increases CFA effects ...

The impact of in vitro chemosensitivity test-guided platinum-based adjuvant chemotherapy on the surgical outcomes of patients undergoing complete resection for locally advanced non-small cell lung cancer (NSCLC) has yet to be elucidated. In the present study, the utility of adjuvant chemotherapy based on the collagen gel droplet embedded culture drug sensitivity test (CD-DST) in patients with p...

OBJECTIVES We evaluate the long-term results of a randomized clinical trial in patients with advanced stages (III and IV) of follicular lymphoma using chemotherapy or combined therapy (chemotherapy following by adjuvant radiotherapy in patients with nodal bulky disease). MATERIAL AND METHODS Between 1981 and 1995, patients with follicular lymphoma were treated with combined chemotherapy, most...

Although much progess has been made in the detection and characterization of homocytotropic antibodies, identification of the factors which control their synthesis remains to be determined. To assess the influence of different adjuvants on anti-dinitrophenol (DNP) immunoglobulin E (IgE) antibody responses, rabbits were immunized with adjuvant plus homologous albumin (HRA) heavily substituted wi...

Aromatase inhibitors (AIs) are becoming more widely used than tamoxifen as adjuvant hormonal therapy for postmenopausal women (PMW) with early breast cancer (EBC). It is clear that these drugs offer important efficacy benefits over tamoxifen and differ from tamoxifen in their safety profile. The accepted strategies for adjuvant AI therapy include initial adjuvant treatment following surgery, sw...

introduction: antifertility effects of naturally occuring antisperm antibody (asa) in infertile couples and studies on experimental immunization of various animals with sperm antigens represent asa as an immunocontraceptive target. the effects of different factors on sperm immunogenecity and asa production have been studied and different results have been reported. in this study, whole sperm im...

we conducted this study to determine the level of immunity after vaccination of lambs with whole bodyechinococcus granulosus. to do so, 200 mature e. granulosus parasites, which were kept in 10% formalinefor 8 months, were obtained from the department of parasitology, school of veterinary medicine, ferdowsiuniversity of mashhad. the soluble protein of the parasite was prepared. the sample was h...

background: inflammatory myofibroblastic tumor (imt) is a tumor composed of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. the most common sites of involvement include the lung, liver and orbit, but it has been reported to occur in nearly every site of the body, including oral cavity and soft tissue. although common in other sites, such a tumo...