We introduce a rigorous method to microscopically compute the observables which characterize the thermodynamics and kinetics of rare macromolecular transitions for which it is possible to identify a priori a slow reaction coordinate. In order to sample the ensemble of statistically significant reaction pathways, we define a biased molecular dynamics (MD) in which barrier-crossing transitions ar...

background: haematophagous females of some phlebotomine sandflies are the only natural vectors of leishmania species, the causative agents of leishmaniasis in many parts of the tropics and subtropics, including iran.  we report the presence of phlebotomus (larroussius) major and phlebotomus (adlerius) halepensis in tonekabon (ma­zanderan province) and phlebotomus (larroussius) tobbi in pakdasht...

conclusions surgical and post-surgical findings showed that this segment was not related to the patient’s femur. the foreign segment may have belonged to the other victim of this trauma. introduction femoral shaft fracture is one of the typical bone fractures due to high energy trauma and may occur as an open fracture. some foreign materials may enter the fracture site such as sand, cloth parti...

an analysis of selected fission fragment angular distributions from helium-ion induced fission is made using an exact theoretical expression. theoretical anisotropies obtained with the transition state model are compared with their corresponding values deduced from the statistical scission model. the nuclear moment of inertia extracted from the model calculations are compared with their estimat...

Background: Immunoglobulins are a group of proteins have important role in defense against microorganisms. Human immunoglobulins are divided into five classes: IgA, IgM, IgD, IgE and IgG. Immunoglobulin G (IgG) is the highest abundant antibody in serum and extravascular fluids. The extent of serum IgG is related to severity of several diseases such as infections, so IgG has great diagnostic wor...

Abstract One-dimensional fragment of first-order logic is obtained by restricting quantification to blocks existential (universal) quantifiers that leave at most one variable free. We investigate this over words and trees, presenting a complete classification the complexity its satisfiability problem for various navigational signatures comparing expressive power with other important formalisms....

The Fragment String is a new digital musical instrument designed to reinterpret and reflect upon the sounds of the instruments it is performed in collaboration with. At its core, it samples an input audio signal and allows the performer to replay these samples through a granular resynthesizer. Normally the Fragment String samples an acoustic instrument that accompanies it, but in the absence of...