The osteogenic growth peptide (OGP) is a key factor in the mechanism of the systemic osteogenic response to local bone marrow injury. Recent histologic studies have shown that OGP enhances fracture healing in experimental animals. To assess the effect of systemically administered OGP on the biomechanical and quantitative structural properties of the fracture callus, the present study used an in...

The prediction of healing period of a tibia fracture in humans across limb using first-order mathematical model is demonstrated. At present, fracture healing is diagnosed using X-rays. Recent studies have demonstrated electric stimulation as a diagnostic tool in fracture healing. A DC electric voltage of 0.7 V was applied across the fracture and stabilized with Teflon coated carbon rings and th...

Linear and depressed skull fractures are frequent mechanisms of head injury and are often associated with traumatic brain injury. Accurate knowledge of the fracture of cranial bone can provide insight into the prevention of skull fracture injuries. A set of cranial bone specimens were extracted from 8 crania and, after !CT imaging, the specimens were tested in a three-point bend set-up at dynam...

The present study proposes an integrated computer-aided approach combining femur surface modeling, fracture evidence recover plate creation, and plate modification in order to conduct a parametric investigation of the design of custom plate for a specific patient. The study allows for improving the design efficiency of specific plates on the patients' femur parameters and the fracture informati...

background: some studies have previously shown that geometry of proximal femur can affect the probability of fracture and type of fracture. it happens since the geometry of the proximal femur determines how a force is applied to its different parts. in this study, we have compared proximal femur’s geometric characteristics in femoral neck (fnf), intertrochanteric (itf) and subtrochanteric (stf)...

in this article, failure and fracture mechanisms in an aluminum alloy (which has been used in diesel internal combustion engines), with and without ceramic thermal barrier coatings, have been investigated under isothermal and non-isothermal fatigue loadings. in this research, the base material is an aluminum-silicon-magnesium alloy and the thermal barrier coating includes a metallic bond coat l...

the present article considers the nd:yag pulsed laser welding of 304 stainless steels with two different compositions. the effects of various laser operational parameters and cooling rates on the weld microstructures were considered. the results show that ferritic solidification is produced in the stainless steel with the creq/nieq ratio of 1.7, and austenitic solidification is produced in the ...

Embedded fracture networks in rock masses are studied. The fluid flow in fracture networks with respect to variation of connectivity patterns is analyzed. Lattice Boltzmann method is used to show sensitivity of the permeability and fluid velocity distribution to connectivity patterns of generated fracture networks. Furthermore, fracture networks are mapped into the graphs and the characteristic...

BACKGROUND Hip fractures are mainly caused by accidental falls and trips, which magnify forces in well-defined areas of the proximal femur. Unfortunately, the same areas are at risk of rapid bone loss with ageing, since they are relatively stress-shielded during walking and sitting. Focal osteoporosis in those areas may contribute to fracture, and targeted 3D measurements might enhance hip frac...