نتایج جستجو برای: fractalkine

تعداد نتایج: 925  

2016
Kevin T. Breen Sarah R. Anderson Michael R. Steele David J. Calkins Alejandra Bosco Monica L. Vetter

Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from neurons to myeloid cells. Signaling through its receptor Cx3cr1 has been implicated in multiple neurodegenerative diseases, but the effects on neuron...

2017
Susannah G Ellsworth Bryan M Rabatic Jie Chen Jing Zhao Jeffrey Campbell Weili Wang Wenhu Pi Paul Stanton Martha Matuszak Shruti Jolly Amy Miller Feng-Ming Kong

BACKGROUND/PURPOSE Radiation treatment (RT) stimulates the release of many immunohumoral factors, complicating the identification of clinically significant cytokine expression patterns. This study used principal component analysis (PCA) to analyze cytokines in non-small cell lung cancer (NSCLC) patients undergoing RT and explore differences in changes after hypofractionated stereotactic body ra...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004
Frederick W K Tam Jan-Stephan Sanders Abraham George Tarig Hammad Caroline Miller Tammy Dougan H Terence Cook Cees G M Kallenberg Gill Gaskin Jeremy B Levy Charles D Pusey

BACKGROUND Macrophage infiltration and cytokine production are important in the pathogenesis of crescentic glomerulonephritis in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis. The aim of this study was to investigate whether urinary levels of chemokines, monocyte chemoattractant protein-1 (MCP-1) and fractalkine, were useful tools for non-invasive assessment of renal vasculiti...

Journal: :The Journal of clinical investigation 2015
Stephen E Boag Rajiv Das Evgeniya V Shmeleva Alan Bagnall Mohaned Egred Nicholas Howard Karim Bennaceur Azfar Zaman Bernard Keavney Ioakim Spyridopoulos

BACKGROUND Lymphocytes contribute to ischemia/reperfusion (I/R) injury in several organ systems, but their relevance in ST elevation myocardial infarction (STEMI) is unknown. Our goal was to characterize lymphocyte dynamics in individuals after primary percutaneous coronary intervention (PPCI), assess the prognostic relevance of these cells, and explore mechanisms of lymphocyte-associated injur...

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