1 Department of Clinical Biochemistry and Pathobiochemistry, Charles University 2 Medical School and University Hospital Motol, Prague. 2 Institute of Microbiology, v.v.i. Academy of Sciences of the Czech Republic, Vídeňská 1083, 142 20 Prague. 3 Department of Forensic Medicine and Toxicology, Charles University 1 Medical School , Prague. 4 Neurosurgery Department, Charles University 3 Medical ...

This study describes a method for off-line coupling of thin-layer chromatography (TLC) with electron impact ionization (El)-mass spectrometry for routine determination of pesticides in toxicology and forensic medicine. Six TLC solvent systems are described for 151 different pesticides, and 8-peak mass-spectra generated from full El mass spectra are listed.

D. VAJTR, O. BENADA, J. KUKAČKA, R. PRŮŠA, L. HOUŠŤAVA, P. TOUPALÍK, R. KIZEK Department of Clinical Biochemistry and Pathobiochemistry, Charles University 2 Faculty of Medicine and University Hospital Motol, Prague, Institute of Microbiology, v.v.i. Academy of Sciences of the Czech Republic, Prague, Department of Forensic Medicine and Toxicology, Charles University 1 Faculty of Medicine, Pragu...

Purpose: to investigate the effects of phosphide on some human biological systems in order to find a way to control it and facilitate the prevention and treatment of its poisoning. Materials and Methods: In this study, 67 files of autopsy description, forensic pathology results and forensic toxicology were studied as nominal qualitative variables in terms of each type of histological changes in...

Seyed Mehdi Saberi1, Mohammad-Reza Karimi1, Ardeshir Sheikhazadi2, Mazaher Ghorbani2, Ali Pasha Meysamie3, Zeynab Nasri Nasrabadi2 and Sayed Mahdi Marashi2* 1Department of Psychiatry of Legal Medicine Organization, Tehran, Iran 2 epartment of Forensic Medicine and Toxicology, Tehran University of Medical Sciences, Tehran, Iran 3Department of Community Medicine, Tehran University of Medical Scie...

This article analyzes modern scientific sources on the problems of detection toxic substances in human body, considers existing methods toxicological examination used practical forensic medicine to establish and differentiate acute intoxications with various chemical compounds. Despite presence a large number analysis, diagnosis poisoning is often complicated due lack data circumstances event, ...

There has been an extensive discussion in the forensic toxicology community regarding the effect of trauma on the enzymatic method for ethanol analysis. There is a paucity of information in the literature that addresses this question. This study was designed to compare the Dade Behring Dimension enzymatic method with the reliable gas chromatographic method. The blood samples collected at the sa...

A supercritical fluid extraction (SFE) procedure for the analysis of temazepam from whole blood was developed. Quantitative recoveries were obtained by high-performance liquid chromatography using prazepam as an internal standard and carefully monitoring the extraction temperature and pressure. The results were found to compare well with those obtained by solid-phase extraction techniques, but ...

The Agilent 7000 GC/QQQ system can provide both high selectivity and high sensitivity for the analysis of drugs. Low-level detection and confirmation of large numbers of target drugs in blood extracts is possible in a single run. Combined with information from a single quadrupole screening instrument like the Agilent GC/NPD/MSD/DRS system, a much more complete picture of each sample is now poss...