Virtual Integration Capability is paramount to perform early validation of Cyber Physical Systems. The objective is to guide the systems engineer so as to ensure that the system under design meets multiple criteria through high-fidelity simulation. In this paper, we present an integration scheme that leverages the FMI (Functional Mock-Up interface) standard and the AADL architecture description...

Celsr, also called Flamingo (Fmi) genes encode proteins of the cadherin superfamily. Celsr cadherins are seven-pass transmembrane proteins with nine cadherin repeats in the extracellular domain, and an anonymous intracellular C-terminus. The Drosophila Fmi gene regulates epithelial planar cell polarity and dendritic field deployment. The three Flamingo gene orthologs in man and rodents are name...

In recent years, COVID-19 has spread rapidly among humans. Chest CT is an effective means of diagnosing COVID-19. However, the diagnosis images still depends on doctor's visual judgment and medical experience. This takes a certain amount time may lead to misjudgment. this paper, new algorithm for automatic based chest image data was proposed. The comprehensively uses WE extract features, ELM tr...

The natural complexities of petroleum reservoir systems continue to provide a challenge to geoscientists. In petroleum geology, exploration and production wells are often analysed using image logs and the use of all the available borehole data to completely characterize the reservoir potentials and performance is an important task. The development of reliable interpretation methods is of prime ...

Pravastatin reduce pro-inflammatory mediators in feto-maternal interface (FMi) tissues and minimize PE-like symptoms vitro animal models. Several questions remain regarding the drug’s pharmacokinetics (PK), metabolism, efficacy that cannot be fully answered using traditional 2D cell culture or placental perfusion models prior to clinical trials. We used two distinct microfluidic organ-on-chip (...