It is a pleasure to be able to introduce this second Thematic Series on ‘organo-fluorine chemistry’ within the Beilstein Journal of Organic Chemistry. The series now embeds the subject firmly as a special interest area of the journal. The first series in 2008 presented contributions representing a wide range of organic fluorine chemistry [1-10] and this series continues that trend exploring the...

Fluoride has long been known to influence the activity of various enzymes in vitro. Latterly it has been demonstrated that many effects primarily attributed to fluoride are caused by a synergistic action of fluoride plus aluminum. Fluorinated chemicals are of growing importance, with applications in medicine. Fluorine substitution has profound effects on the properties of organic compounds. The...

We present the reactivity and photochemistry of 2,5-diphenyltellurophene. A change in oxidation state from Te(ii) to Te(iv) occurs by oxidative addition of bromine, chlorine, and fluorine from appropriate halogen sources. Photoreductive halogen elimination is demonstrated using optical absorption spectroscopy and NMR spectroscopy. The photodebromination reaction occurs with 16.9% quantum yield,...

The effect of soluble fluorine species in different concentrations on the catabolic activity of Desulfotomaculum ruminis bacteria has been studied. The fluoride concentrations tolerated by and toxic to the bacteria have been determined. The degree of fluorine species toxicity was found to depend on the form in which fluorine is introduced into the medium and increases in the following order: Na...

Distearoylphosphatidylcholines labeled with gem-difluoro groups at selected positions of the fatty acid chains have been prepared. These lipids were incorporated into sonicated vesicles and were examined by fluorine nuclear magnetic resonance spectroscopy. All spectra are characterized by two well-separated fluorine resonances. Paramagnetic ions added to the exterior solution of vesicles of flu...

We investigated the chlorine plasma reaction with graphene and graphene nanoribbons and compared it with the hydrogen and fluorine plasma reactions. Unlike the rapid destruction of graphene by hydrogen and fluorine plasmas, much slower reaction kinetics between the chlorine plasma and graphene were observed, allowing for controlled chlorination. Electrical measurements on graphene sheets, graph...

We demonstrate the possibility to tune the electronic transport properties of graphene mono-layers and multi-layers by functionalisation with fluorine. For mono-layer samples, with increasing the fluorine content, we observe a transition from electronic transport through Mott variable range hopping (VRH) in two dimensions to Efros-Shklovskii VRH. Multi-layer fluorinated graphene with high conce...

New synthetic methods and fluorinated reagents have been developed,that facilitate the introduction of fluorine or fluorocontaining units into small building blocks, designer compounds, and materials of new and often surprising properties. However,in spite of all these advances, we are still lacking sufficient insight into the fundamental aspects of fluoro-organic chemistry,particularly in the ...