The aim of this project is to investigate the influence of intersection configuration on spreading of contaminants from the vehicle traffic. Experiment was performed by physical modeling method. For crossroad in the shape of perpendicular X, we have measured the mean velocity and concentration field. The flow investigation has confirmed that within the area of corner vortexes the largest accumu...

We develop and analyze a measure-valued fluid model keeping track of parking charging requirements electric vehicles in local distribution grid. show how this arises as an accumulation point appropriately scaled sequence stochastic network models. Our analysis incorporates load-flow models that describe the laws electricity. Specifically, we consider alternating current (AC) linearized Distflow...

Protein synthesis and protein degradation were measured in human NHIK 3025 cells cultured in vitro during and after an acute treatment of extreme hypoxia (less than 4 ppm O2). Furthermore, total protein content per cell was recorded and related to cell cycle phase by coincident measurement of DNA and protein using two-parametric flow cytometry. During hypoxia protein synthesis was reduced and p...

The hemodynamic and the thrombogenic performance of two commercially available bileaflet mechanical heart valves (MHVs)--the ATS Open Pivot Valve (ATS) and the St. Jude Regent Valve (SJM), was compared using a state of the art computational fluid dynamics-fluid structure interaction (CFD-FSI) methodology. A transient simulation of the ATS and SJM valves was conducted in a three-dimensional mode...

BACKGROUND Although many factors and molecules that are closely associated with non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) have been reported, the role of endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) in the pathogenesis of NAFLD/NASH remains unclear. We therefore investigated the role of eNOS-derived NO in NAFLD pathogenesis using system...

Sustained changes in blood flow modulate the size of conduit arteries through structural alterations of the vessel wall that are dependent on the transient accumulation and activation of perivascular macrophages. The leukocytic infiltrate appears to be confined to the adventitia, is responsible for medial remodeling, and resolves once hemodynamic stresses have normalized without obvious intimal...

The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, significant improvements in therapeutic efficacy have yet to be achieved. Imaging of the tumor accumul...

objective(s) doxorubicin (dox), a widely used chemotherapeutic agent can give rise to serve cardiotoxicity by inducing apoptosis. curcumin, the active compound of the rhizome of curcuma longa l. has anti-inflammatory, antioxidant and anti-proliferative activities. curcumin has been identified to increase cytotoxicity in several cancer cell lines in combination with dox, but there is no study ab...

Electro-osmotic flow, the driving of fluid at nano- or micro-scales with electric field, has found numerous applications, ranging from pumping to chemical and biomedical analyses in micro-devices. Electro-osmotic flow exhibits a puzzling hysteretic behavior when two fluids with different concentrations displace one another. The flow rate is faster when a higher concentration solution displaces ...