This study used synchrotron X-ray microtomography on a micron scale to compare three-dimensional (3D) bone ingrowth after implantation of various calcium phosphate bone substitutes in a rabbit model. The advantage of using this new method for the study of biomaterials was then compared with histomorphometry for analysis of interconnection and bone ingrowth. The study focused on the newly formed...

The evaluation of peripheral nerve regeneration is of great interest in clinical as well as in experimental situations. However, there are few techniques that give early and quantitative information on the status of the regeneration process. If quantitative assays would be available, different surgical techniques and medications could be evaluated more accurately in relation to axonal ingrowth ...

There are yet no reports in the literature describing the mechanism of macular hole (MH) formation associated with fibrovascular proliferation in proliferative diabetic retinopathy. We report four cases of MHs in diabetic retinopathy with fibrovascular proliferation; formation of MHs were studied using sequential pre-MH optical coherence tomography (OCT). In Case 1, initial OCT revealed tractio...

OBJECTIVES To describe the features, natural history, and management of an unusual manifestation of ocular von Hippel-Lindau disease in the form of fine vascular proliferation. METHODS Case series of 14 patients with definite or presumed von Hippel-Lindau disease. RESULTS Retinal vascular proliferation consisting of fine superficial vessels was found in 16 eyes of 14 patients with von Hippe...

The stability of cementless acetabular cups depends on a close fit between the components and reamed acetabular cavities to promote bone ingrowth. Cup performance and stability are affected by both design and environmental (patient-dependent and surgical) factors. This study used a statistically based metamodel to determine the relative influences of design and environmental factors on acetabul...

A 20-year old male patient sustained trauma to the right eye by stone 7 years prior to presentation. The patient's right eye had corneal scar, sectoral traumatic cataract and chronic retinal detachment in which retinal detachment repair was done. Seven years later, the patient presented with intracorneal epithelial ingrowth, which was confirmed by histopathology. Conjuctival peritomy was done s...

A 45-year-old patient with a traumatic corneal lamellar laceration who was treated conservatively initially developed an epithelial ingrowth within the flap-stroma interface, causing diminished vision. Confocal microscopy revealed highly refractive bodies without cellular elements at the flap-stroma interface. Treatment comprised surgical debridement of the epithelial sheet from the interface w...

BACKGROUND Pancreatic cancer is often locally invasive. Preoperative staging attempts to identify patients suitable for resection, in order to minimize unnecessary operations. The aim of this study was to assess the improved imaging provided by spiral computed tomography (CT) in the preoperative staging of potentially resectable pancreatic head carcinoma. METHODS In 56 consecutive patients wi...

Various cell types can trans-differentiate to a transfer cell (TC) morphology characterized by deposition of polarized ingrowth walls comprised of a uniform layer on which wall ingrowths (WIs) develop. WIs form scaffolds supporting amplified plasma membrane areas enriched in transporters conferring a cellular capacity for high rates of nutrient exchange across apo- and symplasmic interfaces. Th...