We have determined the protein X-ray crystal structures of four organometallic inhibitors in complex with their target enzyme carbonic anhydrase II. The barrel-shaped hydrophobic ferrocene and ruthenocene moieties have provided a structure-based avenue to better occupy the hydrophobic binding patch within the enzyme active site.

A novel switch-cytosensing strategy has been designed, which is based on the changes of electron transfer efficiency between ferrocene at the end of DNA and the electrode surface before and after cell transfection. This strategy provided a general and convenient method to fabricate efficient electrochemical cell sensors.

The title compound, [Fe(C(11)H(11)N(2)O)(2)], crystallizes with two independent mol-ecules in the asymmetric unit which have have different conformations. In one mol-ecule, the two ferrocene cyclo-penta-dienyl rings are fully eclipsed and the two pyrazole rings are syn to each other; in the other, the two cyclo-penta-dienyl rings are synclinal and the pyrazole rings are anti. In both mol-ecules...

Association constants of a bis-(acetylguanidinium)ferrocene dication to various (di)carboxylates were determined through UV-vis titrations. Association constant values greater than 10(4) M(-1) were determined for both phthalate and maleate carboxylates to the bis-(acetylguanidinium)ferrocene salt in pure water. Density functional theory computations of the binding enthalpy of the rigid carboxyl...

Ferrocene and its derivatives are vital class of organometallic compounds having extensive biological activities. Six novel ferrocene-based thiosemicarbazones have been synthesized through the condensation reaction acetyl ferrocene with differently substituted thiosemicarbazide. Furthermore, we used state-of-the-art computational docking approach to explore theoretical aspects for possible anti...

The synthesis and spectroscopic investigation of an acidochromic phenylenevinylene dye with two ferrocene groups is presented.

Ferrocene is already 70 years old! A respectable age, as claimed by the authors of this Special Issue [...]

Reaction of K(3)P(7), FeCl(2), [NH(4)][B(C(6)H(5))(4)] and 2,2,2-crypt yielded the unprecedented cluster dianion [Fe(HP(7))(2)](2-). This species was characterized by single crystal X-ray diffraction, multielement NMR spectroscopy and electrospray mass-spectrometry. DFT calculations on the dianion were also conducted.

In order to overcome problems with non-uniform iron (Fe) doping in our GaN layers grown by hydride vapor phase epitaxy, we have optimized the construction of our ferrocene doping channel. By pre-heating the hydrogen carrier gas before entering the hot bubbler, a constant Fe supply could be established. Moreover, losses of the precursor gas in the reactor could be minimized by a re-design of the...

The title compound, [Fe(C(5)H(5))(C(30)H(32)O(7)P)], which is an inter-mediate in the synthesis of (R(p))-2-(diphenyl-phos-phino)ferrocene-1-carboxylic acid, crystallizes in the common chiral space group P2(1)2(1)2(1). In general, the mol-ecular geometry is very similar to that of the corresponding 2,1'-bis-(diphenyl-phosphino) congener. The ferrocene unit assumes a regular geometry with the pr...