250 of 250 words) Purpose: To compare the intended versus resultant thickness of laser in situ keratomileusis (LASIK) flaps created with a new femtosecond laser (WaveLight FS200 Femtosecond Laser, WaveLight GmbH, Alcon Laboratories) and to report refractive outcomes at 3 months posttreatment. Setting: Wellington Eye Clinic, Dublin, Ireland Design: Retrospective consecutive case series Methods: ...

PURPOSE To compare intraocular lens (IOL) power calculation and refractive outcome between patients who underwent laser refractive cataract surgery with a femtosecond laser and those with conventional cataract surgery. METHODS In this prospective study, 77 eyes from 77 patients underwent laser refractive cataract surgery (laser group; Alcon LenSx femtosecond laser), and conventional cataract ...

A new terahertz source in air based on the bi-filamentation of femtosecond laser pulses is reported. This THz radiation is one order of magnitude more intense than the transition-Cherenkov THz emission from femtosecond laser filaments reported recently and shows different angular and polarization properties. We attribute it to the emission from a bimodal transmission line created by two plasma ...

With its output wavelength covering the infrared penetrating window of most biological tissues at 1,200-1,250 nm, the femtosecond Cr:forsterite laser shows high potential to serve as an excellent excitation source for the multiphoton fluorescence microscope. Its high output power, short optical pulse width, high stability, and low dispersion in fibers make it a perfect replacement for the curre...

Goal We describe the application of femtosecond laser pulses to image and ablate neuronal tissue for the purpose of automated histology. The histology is accomplished in-situ by serial two-photon imaging of labeled tissue and removal of the imaged tissue with amplified, approximately 100 fs duration pulses, as illustrated schematically in figure 1A. The ablation of tissue with femtosecond, infr...

In this work, focused near-infrared (NIR) femtosecond laser pulses were used to transiently perforate the cellular membrane of targeted human embryonic kidney (HEK) cells and the uptake of extrinsic molecules into the targeted cells was observed. Various cellular responses to the laser treatments were closely analyzed to optimize several experimental parameters such as laser power, exposure tim...

We describe an interferometric method that enables to measure the optical path delay between two consecutive femtosecond laser pulses by way of dispersive interferometry. This method allows a femtosecond laser to be utilized as a source of performing absolute distance measurements to unprecedented precision over extensive ranges. Our test result demonstrates a non-ambiguity range of ~1.46 mm wi...

We present novel results obtained in the fabrication of high-aspect ratio micro-fluidic microstructures chemically etched from fused silica substrates locally exposed to femtosecond laser radiation. A volume sampling method to generate three-dimensional patterns is proposed and a systematic SEM-based analysis of the microstructure is presented. The results obtained gives new insights toward a b...

We demonstrate and characterize a highly linearly polarized (18.8 dB) narrow spectral emission (<80 pm) from an all-fiber Tm laser utilizing femtosecond-laser-written fiber Bragg gratings. Thermally-dependent anisotropic birefringence is observed in the FBG transmission, the effects of which enable both the generation and elimination of highly linearly polarized output. To our knowledge, this i...

We report on fabrication of high-Q lithium niobate (LN) whispering-gallery-mode (WGM) microresonators suspended on silica pedestals by femtosecond laser direct writing followed by focused ion beam (FIB) milling. The micrometer-scale (diameter ~82 μm) LN resonator possesses a Q factor of ~2.5 × 10(5) around 1550 nm wavelength. The combination of femtosecond laser direct writing with FIB enables ...