AIM To determine the most reliable and consistent method and time interval over which to implement a vision impairment quality of life assessment tool. METHODS 117 patients with low vision aged 9-101 years were assigned into three age, sex, and visual function matched groups (n = 39 in each) to answer the Low Vision Quality of Life (LVQOL) questionnaire by post, telephone, or in person. The L...

BACKGROUND Roux-en-Y gastric bypass (RYGB) causes several alterations in gastrointestinal function. We hypothesized that levels of three commonly used fecal tests change after RYGB. METHODS Fecal levels of calprotectin, elastase, and alpha-1-antitrypsin were determined in 122 patients without signs of gastrointestinal disease 1 to 2 years after RYGB. Medians, distribution of values, and the p...

Fecal microRNAs (miRNAs) are increasingly explored as non-invasive markers of colorectal cancer (CRC). However, its holistic profile in Asian CRC patients remains elusive. In the present study, the global human fecal miRNAs in Asian Chinese CRC patients was assayed to elucidate novel diagnostic fecal markers. Additionally, the influence of blood in stool on fecal miRNA levels was investigated f...

Fecal biomarkers have emerged as important tools to assess intestinal inflammation and enteropathy. The aim of this study was to investigate the correlations between the fecal markers, myeloperoxidase (MPO), lactoferrin (FL), calprotectin (FC) and lipocalin-2 (Lcn-2), and to compare differences by breastfeeding status as well as normalization by fecal protein or by fecal weight. Simultaneous, q...

Prior to implementation of volatile organic compound (VOC) analysis in clinical practice, substantial challenges, including methodological, biological and analytical difficulties are faced. The aim of this study was to evaluate the influence of several sampling conditions and environmental factors on fecal VOC profiles, analyzed by an electronic nose (eNose). Effects of fecal sample mass, water...

AIM To determine the psychometric properties of the total Vaizey score and its individual items. METHODS The study was conducted as part of a prospective cohort study assessing the outcome of pelvic floor rehabilitation in patients with fecal incontinence. RESULTS One hundred ninety-four patients were analyzed, 53 of whom provided data on the global perceived effect (GPE) score. Pelvic floo...

AIM The aim of the present study was to conduct a psychometric validation of the Japanese version of the FIQL (JFIQL). METHOD A retrospective analysis of data from the JFIQL was conducted. Wexner scores and Faecal Incontinence Severity Index (FISI) scores were collected prospectively in patients with faecal incontinence who visited our centre between 2008 and 2009. For convergent validity, th...

background : fecal incontinence is defined as the involuntary loss of fecal material. fecal incontinence is a particularly embarrassing and distressing condition with significant medical, social and economic implications. the purpose of this article is to review the relevant the role of pelvic floor muscle dysfunction in fecal incontinence. materials and mthods : we performed a literature searc...

Fecal incontinence is defined as the passage of stools in an inappropriate place. This frustrating symptom is a source of considerable distress and embarrassment for the child and his/her family. Pediatric fecal incontinence can be divided into 2 main categories: (1) organic fecal incontinence, e.g., resulting from anorectal malformations or neurogenic abnormalities, and (2) functional fecal in...